Grześko Joanna, Elias Marek, Maczyńska Beata, Kasprzykowska Urszula, Tłaczała Magdalena, Goluda Marian
Klinika Ginekologii II Katedry Ginekologii i Połoznictwa AM we Wrocławiu.
Med Dosw Mikrobiol. 2007;59(2):169-75.
The group of organisms commonly referred to as genital mycoplasmas comprise species most often found in genitourinary tract of sexually active adults as common commensal inhabitants, or pathogens which can possibly cause many different pathologies like: non-gonococcal urethritis, bacterial vaginosis, cervicitis, endometritis or pelvic inflammatory disease. The problem of their morbidity and the possible influence they have on human fertility is still not clear. The aim of this study was to find out whether two investigated species- Ureaplasma urealyticum and Mycoplasma hominis can be detect more often in a group of infertile women. 74 women participated in the study and were assigned to one of 2 groups of patients: infertile women and fertile women without any sign of genital tract infection. Swabs from the cervical canal of the uterus and the fluid from the Douglas pouch were taken during the gynecological examination and laparoscopic procedure. Two diagnostic methods were used: biochemical method- commercial diagnostic kit- Mycoplasma IST 2 and PCR method. The results showed that Ureaplasma urealyticum and Mycoplasma hominis were detected among both fertile and infertile women with nearly the same frequency, much more often in cervical canal than in the Douglas pouch. Ureaplasma urealyticum was more common pathogen than Mycoplasma hominis in both groups and locations. The achieved results point out that the role of genital mycoplasmas in human infertility is still unclear and require further investigations.
通常被称为生殖支原体的这组生物体包括最常作为常见共生菌在性活跃成年人的泌尿生殖道中发现的物种,或者可能导致许多不同病症的病原体,如:非淋菌性尿道炎、细菌性阴道病、宫颈炎、子宫内膜炎或盆腔炎。它们的发病率问题以及它们对人类生育能力可能产生的影响仍不明确。本研究的目的是找出在一组不孕女性中是否能更频繁地检测到两种被研究的物种——解脲脲原体和人型支原体。74名女性参与了该研究,并被分配到两组患者中的一组:不孕女性和无任何生殖道感染迹象的有生育能力的女性。在妇科检查和腹腔镜手术期间,从子宫颈管采集拭子,并从Douglas窝采集液体。使用了两种诊断方法:生化方法——商业诊断试剂盒——Mycoplasma IST 2和聚合酶链反应(PCR)方法。结果表明,在有生育能力的女性和不孕女性中,解脲脲原体和人型支原体的检测频率几乎相同,在子宫颈管中的检测频率比在Douglas窝中高得多。在两组和两个部位,解脲脲原体都是比人型支原体更常见的病原体。所取得的结果指出,生殖支原体在人类不孕中的作用仍不明确,需要进一步研究。