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全球范围内的心血管疾病:确定研究与实践的前进方向

Cardiovascular disease on a global scale: defining the path forward for research and practice.

作者信息

Mark Daniel B, Van de Werf Frans J, Simes R John, White Harvey D, Wallentin Lars C, Califf Robert M, Armstrong Paul W

机构信息

Division of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University Medical Center, PO Box 17969, Durham, NC 27715, USA.

出版信息

Eur Heart J. 2007 Nov;28(21):2678-84. doi: 10.1093/eurheartj/ehm411. Epub 2007 Oct 16.

Abstract

During the 2006 World Congress of Cardiology meeting in Barcelona, the Virtual Coordinating Centre for Global Collaborative Cardiovascular Research (VIGOUR) group held a symposium examining potential approaches to understanding and controlling the explosive worldwide growth of cardiovascular disease and its attendant morbidity and mortality. Over the last 20 years, the global nature of many problems in health care has become much more evident. In the realm of health, this has meant that countries across the globe have started to experience the same kinds of behavioural shifts (overeating, reduced physical activity and smoking), and with them massive increases in cardiovascular risk factors, observed over the last century particularly in North America and Western Europe. This VIGOUR symposium focused on what actions can be taken now to prepare for this future in which prevention and treatment of cardiovascular disease will be a major public health issue in a much larger proportion of the world's countries. The participants focused on four major areas where they saw important opportunities: (i) the development of high quality, contemporaneous data sources that can be used to study and improve the processes, treatments and outcomes of cardiovascular diseases globally; (ii) the feasibility and resource/health economic implications of any proposed potential solutions need to be carefully defined; (iii) models/systems must be identified that can be used to guide effective interventions targeting health problems of large populations at an affordable price; (iv) academic research organizations need to assume a more active role in the health-care system both through their traditional activities in discovery research and developing evidence-based medicine along with translation of research findings into effective interventions that improve the public health.

摘要

在2006年于巴塞罗那召开的世界心脏病学大会期间,全球心血管研究协作虚拟协调中心(VIGOUR)小组举办了一场研讨会,探讨理解和控制心血管疾病在全球范围内迅猛增长及其相关发病率和死亡率的潜在方法。在过去20年里,医疗保健领域许多问题的全球性变得更加明显。在健康领域,这意味着全球各国开始经历相同类型的行为转变(暴饮暴食、体力活动减少和吸烟),随之而来的是心血管危险因素大幅增加,这种情况在上个世纪尤其在北美和西欧出现过。这次VIGOUR研讨会聚焦于现在可以采取哪些行动来为这样一个未来做准备,即在世界上更大比例的国家中,心血管疾病的预防和治疗将成为一个主要的公共卫生问题。与会者聚焦于他们认为有重要机遇的四个主要领域:(i)开发高质量的同期数据源,可用于研究和改善全球心血管疾病的诊疗过程、治疗方法及治疗结果;(ii)任何提议的潜在解决方案的可行性以及资源/健康经济影响都需要仔细界定;(iii)必须确定能够以可承受的价格用于指导针对大量人群健康问题的有效干预措施的模型/系统;(iv)学术研究组织需要在医疗保健系统中发挥更积极的作用,既要通过其在探索性研究和发展循证医学方面的传统活动,还要将研究结果转化为改善公众健康的有效干预措施。

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