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A Live Cell Protein Complementation Assay for ORFeome-Wide Probing of Human HOX Interactomes.
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Characterizing Hox genes in mayflies (Ephemeroptera), with Hexagenia limbata as a new mayfly model.
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Hox genes collaborate with helix-loop-helix factor Grainyhead to promote neuroblast apoptosis along the anterior-posterior axis of the Drosophila larval central nervous system.
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Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors.
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Roles of Hox Genes in the Assembly of Neuromuscular Networks and Behavior.
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The Hox protein conundrum: The "specifics" of DNA binding for Hox proteins and their partners.
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A six-amino-acid motif is a major determinant in functional evolution of HOX1 proteins.
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本文引用的文献
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Hox cofactors in vertebrate development.
Dev Biol. 2006 Mar 15;291(2):193-206. doi: 10.1016/j.ydbio.2005.10.032. Epub 2006 Mar 3.
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Modulating Hox gene functions during animal body patterning.
Nat Rev Genet. 2005 Dec;6(12):893-904. doi: 10.1038/nrg1726.
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Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax.
Development. 2005 Dec;132(23):5271-81. doi: 10.1242/dev.02138.
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Direct integration of Hox and segmentation gene inputs during Drosophila development.
Nature. 2004 Oct 7;431(7009):653-9. doi: 10.1038/nature02946.
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Loss of function but no gain of function caused by amino acid substitutions in the hexapeptide of Hoxa1 in vivo.
Mol Cell Biol. 2004 Oct;24(19):8567-75. doi: 10.1128/MCB.24.19.8567-8575.2004.
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In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster.
Dev Biol. 2003 Dec 1;264(1):77-90. doi: 10.1016/j.ydbio.2003.07.020.
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Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior.
Genes Dev. 2003 Aug 15;17(16):2060-72. doi: 10.1101/gad.1103303.
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The hexapeptide and linker regions of the AbdA Hox protein regulate its activating and repressive functions.
Dev Cell. 2003 May;4(5):761-8. doi: 10.1016/s1534-5807(03)00126-6.
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Specificity of Distalless repression and limb primordia development by abdominal Hox proteins.
Dev Cell. 2002 Oct;3(4):487-98. doi: 10.1016/s1534-5807(02)00257-5.
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Hox repression of a target gene: extradenticle-independent, additive action through multiple monomer binding sites.
Development. 2002 Jul;129(13):3115-26. doi: 10.1242/dev.129.13.3115.
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