紫背金盘地上部分中的其他黄酮醇和环烯醚萜苷类化合物。

Further flavonol and iridoid glycosides from Ajuga remota aerial parts.

作者信息

Manguro Lawrence Onyango Arot, Ogur Joseph Achola, Okora Dennis Magio, Wagai Samuel Otieno, Lemmen Peter

机构信息

Chemistry Department, Maseno University, Maseno, Kenya.

出版信息

J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):617-29. doi: 10.1080/10286020600979480.

DOI:10.1080/10286020600979480

PMID:17943556

Abstract

Five new iridoid glycosides characterised as 6-keto-8-acetylharpagide (1), 6,7-dehydro-8-acetylharpagide (2), 7,8-dehydroharpagide (3), 8-acetylharpagide-6-O-beta-glucoside (4), harpagide-6-O-beta-glucoside (5) together with three flavonol glycosides, myricetin 3-O-rutinoside-4'-O-rutinoside (6), myricetin 3-O-rutinoside-3'-O-rutinoside (7) and isorhamnetin 3-O-rutinoside-7-O-rutinoside-4'-O-beta-glucoside (8) have been isolated from the aerial parts of Ajuga remota. Also isolated were two known compounds ajugarin IV and ajugarin V. Their structures were established using spectroscopic methods including UV, IR, FAB-MS, HR-MS, 1D and 2D NMR techniques.

摘要

从远距筋骨草地上部分分离得到了5种新的环烯醚萜苷，分别鉴定为6-酮基-8-乙酰哈帕苷（1）、6,7-脱氢-8-乙酰哈帕苷（2）、7,8-脱氢哈帕苷（3）、8-乙酰哈帕苷-6-O-β-葡萄糖苷（4）、哈帕苷-6-O-β-葡萄糖苷（5），以及3种黄酮醇苷，杨梅素3-O-芸香糖苷-4'-O-芸香糖苷（6）、杨梅素3-O-芸香糖苷-3'-O-芸香糖苷（7）和异鼠李素3-O-芸香糖苷-7-O-芸香糖苷-4'-O-β-葡萄糖苷（8）。还分离得到了两种已知化合物筋骨草苷IV和筋骨草苷V。通过紫外光谱（UV）、红外光谱（IR）、快原子轰击质谱（FAB-MS）、高分辨质谱（HR-MS）、一维和二维核磁共振（1D和2D NMR）技术等光谱方法确定了它们的结构。