Fujii Takahiro, Ono Akiko, Fu Kuang-I
TF Clinic, Ginza, Tokyo, Japan.
Gastrointest Endosc. 2007 Dec;66(6):1215-20. doi: 10.1016/j.gie.2007.05.054. Epub 2007 Oct 22.
Although EMR has been proven to be a safe procedure, the risk of hemorrhage and perforation increases with the size of the resected lesion. To overcome such complications, we previously reported a technique using an endoloop and metal clips to close large mucosal defects after EMR. This procedure, however, requires a 2-channel colonoscope, which is not always available.
Our purpose was to demonstrate the feasibility of mucosal defect closure by using a conventional single-channel colonoscope, a specially designed figure-of-8-shaped stainless steel ring (8-ring) and resolution clips.
Pilot study.
Private outpatient clinic.
A total of 10 patients with 10 lesions underwent this procedure for closure after EMR.
After EMR, a Resolution clip (Boston Scientific, Natick, Mass) was placed through 1 hole of the 8-ring and then attached to normal mucosa near 1 side of the resection site. Another resolution clip was inserted through the remaining hole of the device and clipped in the normal mucosa on the other side, thus providing complete closure. To strengthen the closure, conventional endoclips were also placed.
Technical feasibility of endoscopic closure of the mucosal defect after EMR and complications associated with endoscopic procedures.
Mean size of resected lesion was 16.3 mm. All the defects were successfully closed without any complication such as delayed bleeding or perforation.
Further study is needed to examine the maximum size of defects that can be closed with this method.
Defects after EMR can be treated successfully with this simple technique.
尽管内镜黏膜切除术(EMR)已被证明是一种安全的手术,但出血和穿孔的风险会随着切除病变的大小而增加。为了克服这些并发症,我们之前报道了一种在EMR后使用内镜圈套器和金属夹来闭合大的黏膜缺损的技术。然而,该手术需要双通道结肠镜,而这种设备并非总是可用。
我们的目的是证明使用传统单通道结肠镜、一种特殊设计的8字形不锈钢环(8环)和可分离夹闭合黏膜缺损的可行性。
前瞻性研究。
私立门诊诊所。
共有10例患有10处病变的患者在EMR后接受了该闭合手术。
EMR后,将一个可分离夹(波士顿科学公司,马萨诸塞州纳蒂克)通过8环的一个孔置入,然后夹在切除部位一侧附近的正常黏膜上。另一个可分离夹通过该装置的其余孔插入并夹在另一侧的正常黏膜上,从而实现完全闭合。为加强闭合效果,还放置了传统的内镜夹。
EMR后内镜闭合黏膜缺损的技术可行性以及与内镜手术相关的并发症。
切除病变的平均大小为16.3毫米。所有缺损均成功闭合,未出现任何诸如延迟出血或穿孔等并发症。
需要进一步研究以检查用该方法可闭合的缺损的最大尺寸。
用这种简单技术可成功治疗EMR后的缺损。