用于检测心脏和肺部疾病的CT容积与双能数字X线摄影的自动配准
Automatic registration of CT volumes and dual-energy digital radiography for detection of cardiac and lung diseases.
作者信息
Fei Baowei, Chen Xiang, Wang Hesheng, Sabol John M, DuPont Elena, Gilkeson Robert C
机构信息
Dept. of Radiol. & Biomed. Eng., Case Western Reserve Univ., Cleveland, OH 44106, USA.
出版信息
Conf Proc IEEE Eng Med Biol Soc. 2006;2006:1976-9. doi: 10.1109/IEMBS.2006.259888.
We are investigating image processing and analysis techniques to improve the ability of dual-energy digital radiography (DR) for the detection of cardiac calcification. Computed tomography (CT) is an established tool for the diagnosis of coronary artery diseases. Dual-energy digital radiography could be a cost-effective alternative. In this study, we use three-dimensional (3D) CT images as the "gold standard" to evaluate the DR X-ray images for calcification detection. To this purpose, we developed an automatic registration method for 3D CT volumes and two-dimensional (2D) X-ray images. We call this 3D-to-2D registration. We first use a 3D CT image volume to simulate X-ray projection images and then register them with X-ray images. The registered CT projection images are then used to aid the interpretation dual-energy X-ray images for the detection of cardiac calcification. We acquired both CT and X-ray images from patients with coronary artery diseases. Experimental results show that the 3D-to-2D registration is accurate and useful for this new application.
我们正在研究图像处理和分析技术，以提高双能数字X线摄影（DR）检测心脏钙化的能力。计算机断层扫描（CT）是诊断冠状动脉疾病的既定工具。双能数字X线摄影可能是一种具有成本效益的替代方法。在本研究中，我们使用三维（3D）CT图像作为“金标准”来评估用于钙化检测的DR X线图像。为此，我们开发了一种用于3D CT体积和二维（2D）X线图像的自动配准方法。我们将此称为3D到2D配准。我们首先使用3D CT图像体积来模拟X线投影图像，然后将它们与X线图像配准。然后，配准后的CT投影图像用于辅助解读双能X线图像以检测心脏钙化。我们从冠状动脉疾病患者那里获取了CT和X线图像。实验结果表明，3D到2D配准对于这种新应用是准确且有用的。
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