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使用360度自由空间荧光分子断层扫描技术对小鼠进行体内肺癌成像。

In-vivo lung cancer imaging in mice using 360 degrees free-space fluorescence molecular tomography.

作者信息

Deliolanis Nikolaos, Lasser Tobias, Niedre Mark, Soubret Antoine, Ntziachristos Vasilis

机构信息

Laboratory for Bio-optics & Molecular Imaging, Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Charlestown 02129, USA.

出版信息

Conf Proc IEEE Eng Med Biol Soc. 2006;2006:2370-2. doi: 10.1109/IEMBS.2006.260683.

DOI:10.1109/IEMBS.2006.260683
PMID:17946109
Abstract

We present the development and performance characteristics of a free-space fluorescence tomography system. The imaging system can capture complete angle projections of photons propagating through tissue in transillumination using a CCD camera. Experimental data on imaging lung cancer are presented. Overall, this imaging approach can offer unprecedented imaging performance in fluorescence molecular tomography of small animals.

摘要

我们展示了一种自由空间荧光断层扫描系统的开发及性能特征。该成像系统能够使用电荷耦合器件（CCD）相机在透射照明下捕获穿过组织传播的光子的完整角度投影。文中给出了关于肺癌成像的实验数据。总体而言，这种成像方法在小动物荧光分子断层扫描中可提供前所未有的成像性能。

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