Burnier Michel
Service de néphrologie, Département de médecine, CHUV, 1011 Lausanne.
Rev Med Suisse. 2007 Sep 12;3(124):2007-10.
The increasing use of 24 h ambulatory blood pressure monitoring provides important information on daytime and on nighttime pressures. Today, there is no clear recommendation on how to manage an increase in nighttime blood pressure. The goal of this article is to review the normal values of nighttime blood pressure and to discuss the most recent scientific data linking nocturnal blood pressure with an increased cardiovascular risk. We have now a good evidence that elevated nocturnal pressures are associated with an increased risk of developing cardiac, renal and cerebral complications. However, no clinical study has demonstrated the interest of treating specifically nighttime blood pressure. Nonetheless, in high risk patients, it may be wise to consider a treatment that lowers blood pressure as effectively during the day and during the night.
24小时动态血压监测的使用日益增加,它能提供有关日间和夜间血压的重要信息。目前,对于如何处理夜间血压升高尚无明确的建议。本文的目的是回顾夜间血压的正常值,并讨论将夜间血压与心血管风险增加相联系的最新科学数据。我们现在有充分的证据表明,夜间血压升高与发生心脏、肾脏和脑部并发症的风险增加有关。然而,尚无临床研究证明专门治疗夜间血压的益处。尽管如此,对于高危患者,考虑一种能在白天和夜间同样有效降低血压的治疗方法可能是明智的。