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[血管内镍钛诺支架在治疗胸廓出口综合征锁骨下静脉受压中的应用]

[The use of intravascular nitinol stents in the treatment of subclavian vein compression for thoracic outlet syndrome].

作者信息

Pupka Artur, Szyber Przemysław P, Garcarek Jerzy, Szyber Piotr

机构信息

Katedra i Klinika Chirurgii Naczyniowej, Ogólnej i Transplantacyjnej AM we Wrocławiu.

出版信息

Polim Med. 2007;37(2):51-5.

Abstract

AIM

The purpose of this study is to evaluate the multimodal treatment (thrombolysis, anticoagulation and surgical decompression) of subclavian-axillary vein thrombosis (Paget-Schroetter syndrome) and possibility of shortening of time of therapy.

MATERIAL AND METHODS

In this paper 23 patients with Paget-Schroetter syndrome in Department of Vascular, General and Transplantological Surgery is presented. Thrombolysis with rt-PA, anticoagulation with heparin and intra venous angioplasty with the use intravascular stent, and operation with resection of the first rib in the treatment of subclavian vein thrombosis was used. During the follow up period the patients were divided into two groups: group I (13 patients) with traditional surgical decompression after 3-4 months (potential risk of hemorage) and group II (10 patients) with early surgical treatment (median 8 days). Long-term follow-up was obtained by chart review and asking patients to complete the DASH (Disabilities of the Arm, Shoulder and Hand) questionnaire that was developed by the American Academy of Orthopedic Surgeons.

RESULTS

Complete revascularization with venous thrombolysis was achived in all patients. Decompresion with transaxillary resection of first rib and venous revascularization were performed in the same procedure in all patients. Statistical difference were not found in both groups. Most patients report no disability of upper limb at work and sport activity.

CONCLUSIONS

Multimodal treatment of Paget-Schroetter syndrome (thrombolysis, the use of intravascular stents and early thoracic outlet decompression) can be used as a optimal of therapeutic method to subclavian vein thrombosis. The advantages of immediate surgical treatment are a promotion of rapid resumption of athletic activities.

摘要

目的

本研究旨在评估锁骨下-腋静脉血栓形成(佩吉特-施罗特综合征)的多模式治疗(溶栓、抗凝和手术减压)以及缩短治疗时间的可能性。

材料与方法

本文介绍了血管、普通及移植外科的23例佩吉特-施罗特综合征患者。采用rt-PA溶栓、肝素抗凝、血管内支架置入的静脉血管成形术以及切除第一肋治疗锁骨下静脉血栓形成。在随访期间,患者被分为两组:第一组(13例患者)在3-4个月后进行传统手术减压(有出血潜在风险),第二组(10例患者)进行早期手术治疗(中位时间为8天)。通过查阅病历并要求患者完成美国矫形外科医师学会制定的DASH(上肢、肩部和手部功能障碍)问卷来进行长期随访。

结果

所有患者均通过静脉溶栓实现了完全血管再通。所有患者均在同一手术中进行了经腋路切除第一肋减压和静脉血管再通。两组之间未发现统计学差异。大多数患者报告在工作和体育活动中上肢无功能障碍。

结论

佩吉特-施罗特综合征的多模式治疗(溶栓、使用血管内支架和早期胸廓出口减压)可作为锁骨下静脉血栓形成的最佳治疗方法。早期手术治疗的优点是促进体育活动的快速恢复。

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