Uurto Ilkka, Hannukainen Jorma, Aarnio Pertti
Department of Surgery, Satakunta Central Hospital, Pori; and Department of Vascular Surgery, Tampere University Hospital, Tampere, Finland.
Dermatol Surg. 2007 Nov;33(11):1334-9; discussion 1339. doi: 10.1111/j.1524-4725.2007.33285.x.
Varicose veins are a common disorder and many treatment methods are available.
The aim of this study was to evaluate the short-term efficacy of foam sclerotherapy and the safety of performing the treatment in an outpatient clinic without ultrasound guidance. METHODS This was a prospective, nonrandomized study with foam sclerotherapy. All the patients were assessed before and after the procedure with a CEAP (Clinical, Etiology, Anatomy, Pathology) class and clinical score. At the same visit, duplex scanning was performed to evaluate the anatomic distribution of the varicose disease. The mean age of the patients was 49.2 years (SD,+/-10.6 years; median, 50.0 years). Altogether 41% of the legs had undergone a previous operation and 24% were recurrences. The follow-up time was 3 months.
Twenty-five patients with 27 legs were treated successfully using foam sclerotherapy without ultrasound guidance. Twenty-one cases (78%) involved the great saphenous vein and 6 cases (22%) involved the small saphenous vein. The mean bandage time was 7.7 days (SD,+/-2.50 days; median, 8.50 days). The CEAP score decreased 73% after the procedure from 2.61 (SD,+/-0.80; median, 2.0) to 0.71 (SD,+/-0.95; median, 0; p<.001). and the mean clinical score decreased 45% from 4.45 (SD,+/-1.96; median, 4.0) to 2.46 (SD,+/-1.50; median, 2.0; p<.001), respectively. Three months after the treatment, duplex scanning showed saphenofemoral reflux in 63% of the legs and saphenopopliteal reflux in 40% of the legs. The most common complication was postoperative thrombophlebitis (66%). Other minor complications included pain (38%) and hematoma (4%). There were no major complications. Subjectively, 71% of the patients assessed the procedure as good or excellent and 29% as acceptable or poor.
Foam sclerotherapy is also an effective and safe procedure when performed without duplex guidance. Thrombophlebitis is frequent when using a high concentration of polidocanol and a short bandage time. The high frequency of saphenofemoral and saphenopopliteal junction reflux after the procedure can have a negative effect on the long-term results.
静脉曲张是一种常见疾病,有多种治疗方法。
本研究旨在评估泡沫硬化疗法的短期疗效以及在无超声引导的门诊进行该治疗的安全性。
这是一项采用泡沫硬化疗法的前瞻性、非随机研究。所有患者在治疗前后均采用CEAP(临床、病因、解剖、病理)分级和临床评分进行评估。在同一次就诊时,进行双功扫描以评估静脉曲张疾病的解剖分布。患者的平均年龄为49.2岁(标准差,±10.6岁;中位数,50.0岁)。总共41%的下肢曾接受过手术,24%为复发病例。随访时间为3个月。
25例患者的27条下肢在无超声引导下成功接受了泡沫硬化疗法治疗。21例(78%)累及大隐静脉,6例(22%)累及小隐静脉。平均包扎时间为7.7天(标准差,±2.50天;中位数,8.50天)。治疗后CEAP评分从2.61(标准差,±0.80;中位数,2.0)降至0.71(标准差,±0.95;中位数,0;p<0.001),下降了73%,平均临床评分从4.45(标准差,±1.96;中位数,4.0)降至2.46(标准差,±1.50;中位数,2.0;p<0.001)。治疗3个月后,双功扫描显示63%的下肢存在股隐静脉反流,40%的下肢存在腘隐静脉反流。最常见的并发症是术后血栓性静脉炎(66%)。其他轻微并发症包括疼痛(38%)和血肿(4%)。无重大并发症。主观上,71%的患者对该治疗评价为良好或优秀,29%评价为可接受或较差。
在无双功引导的情况下进行泡沫硬化疗法也是一种有效且安全的方法。使用高浓度聚多卡醇且包扎时间短时血栓性静脉炎较为常见。治疗后股隐静脉和腘隐静脉交界处反流的高发生率可能对长期效果产生负面影响。