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[未行胆囊切除术出院的胆结石患者会怎样?222例初发未治疗胆结石患者的随访]

[What happens to gallstone patients discharged without cholecystectomy? Follow-up of 222 consecutive patients with initially untreated gallstones].

作者信息

Eriksen Jens Ravn, Boel Thomas, Schulze Svend, Kristiansen Viggo B

机构信息

Glostrup Hospital, Kirurgisk Afdeling D.

出版信息

Ugeskr Laeger. 2007 Oct 22;169(43):3649-52.

Abstract

INTRODUCTION

The aim of this study was to investigate the cholecystectomy rate and rate of gallstone-related complications in patients formerly seen and discharged without operation from the Clinic for Day-Surgery, Glostrup University Hospital, Denmark.

MATERIALS AND METHODS

From January 2000 to December 2002 a total of 222 patients with gallstones were discharged without operation (lap. cholecystectomy) from the day-surgery clinic. All admittances and surgical procedures in the follow-up period were identified by reading patient files and strategic searches in the National Patient Register in which all operations in Denmark are registered.

RESULTS

The median follow-up period was 37 months (range 5-62 months). 25% of patients were operated in the follow-up period (cholecystectomy, n = 54, gallstone ileus, n=1). 13% had gallstone-related complications in the follow-up period. 9 patients had one or more endoscopic retrograde cholangiographies. There was no mortality or serious surgical complications.

CONCLUSION

There is a lack of objective criteria for cholecystectomy in symptomatic cholecystolithiasis. The national guidelines in Denmark advocate cholecystectomy only in patients with socially disabling pain attacks. These guidelines are followed in our department and the strategy seems acceptable and patient-friendly, although the optimal treatment strategy for patients with symptomatic gallstone disease is still unknown.

摘要

引言

本研究旨在调查丹麦格罗斯特鲁普大学医院日间手术诊所曾就诊且未经手术出院的患者的胆囊切除术率及胆结石相关并发症发生率。

材料与方法

2000年1月至2002年12月期间,共有222例胆结石患者从日间手术诊所未经手术(腹腔镜胆囊切除术)出院。通过查阅患者病历并在国家患者登记处进行策略性检索,确定随访期间的所有入院情况和手术操作,丹麦所有手术均在该登记处登记。

结果

中位随访期为37个月(范围5 - 62个月)。25%的患者在随访期间接受了手术(胆囊切除术,n = 54;胆石性肠梗阻,n = 1)。13%的患者在随访期间出现胆结石相关并发症。9例患者接受了一次或多次内镜逆行胰胆管造影术。无死亡病例或严重手术并发症。

结论

对于有症状的胆囊结石,缺乏胆囊切除术的客观标准。丹麦的国家指南仅提倡对疼痛发作导致社交障碍的患者进行胆囊切除术。我们科室遵循这些指南,该策略似乎是可接受且对患者友好的,尽管有症状胆结石疾病患者的最佳治疗策略仍不明确。

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