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非洲姑息性放疗的实践模式,第1部分:骨转移和脑转移

Patterns of practice of palliative radiotherapy in Africa, Part 1: Bone and brain metastases.

作者信息

Sharma Vinay, Gaye Papa Macoumba, Wahab Sherif Abdel, Ndlovu Ntokozo, Ngoma Twalib, Vanderpuye Verna, Sowunmi Anthonia, Kigula-Mugambe Joseph, Jeremic Branislav

机构信息

Department of Radiation Oncology, Johannesburg Hospital, University of Witwatersrand, Johannesburg, South Africa.

出版信息

Int J Radiat Oncol Biol Phys. 2008 Mar 15;70(4):1195-201. doi: 10.1016/j.ijrobp.2007.07.2381. Epub 2007 Oct 29.

Abstract

PURPOSE

To provide data on the pattern of practice of palliative radiotherapy (RT) on the African continent.

METHODS AND MATERIALS

A questionnaire was distributed to participants in a regional training course of the International Atomic Energy Agency in palliative cancer care and sent by e-mail to other institutions in Africa. Requested information included both infrastructure and human resources available and the pattern of RT practice for metastatic and locally advanced cancers.

RESULTS

Of 35 centers contacted, 24 (68%) completed the questionnaire. Although RT is used by most centers for most metastatic cancers, liver and lung metastases are treated with chemotherapy. Of 23 centers, 14 (61%) had a single RT regimen as an institutional policy for treating painful bone metastases, but only 5 centers (23%) of 23 used 8 Gy in 1 fraction. Brain metastases were being treated by RT to the whole brain to 30 Gy in 10 fractions, either exclusively (n=13, 56%) or in addition to the use of 20 Gy in 5 fractions (n=3, 14%).

CONCLUSION

Radiotherapy is a major component of treatment of cancer patients in African countries. There is consensus among few centers for treatment schedules for almost all sites regarding time and dose-fractionation characteristics of RT regimens used and/or indications for the use of RT in this setting.

摘要

目的

提供关于非洲大陆姑息性放疗(RT)实践模式的数据。

方法和材料

向国际原子能机构姑息性癌症护理区域培训课程的参与者发放了问卷,并通过电子邮件发送给非洲的其他机构。所需信息包括可用的基础设施和人力资源以及转移性和局部晚期癌症的放疗实践模式。

结果

在联系的35个中心中,24个(68%)完成了问卷。尽管大多数中心对大多数转移性癌症使用放疗,但肝转移和肺转移采用化疗。在23个中心中,14个(61%)将单一放疗方案作为治疗疼痛性骨转移的机构政策,但23个中心中只有5个(23%)采用1次分割给予8 Gy。脑转移采用全脑放疗,10次分割给予30 Gy,要么单独使用(n = 13,56%),要么在使用5次分割给予20 Gy之外联合使用(n = 3,14%)。

结论

放疗是非洲国家癌症患者治疗的主要组成部分。几乎所有部位的放疗方案在放疗时间和剂量分割特点以及在这种情况下使用放疗的指征方面,少数中心之间存在共识。

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