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[正常儿童及生长发育迟缓儿童睡眠期间生长激素、促卵泡生成素和促黄体生成素的分泌情况]

[Secretions of GH, FSH and LH during sleep of the normal child and the child with retarded growth].

作者信息

Besset A, Amilhau D, Bonardet A, Descomps B, Billiard M, Passouant P

出版信息

C R Seances Soc Biol Fil. 1975;169(6):1551-61.

PMID:179677
Abstract

In normal children the major GH release begins during NREM sleep of first cycle. At puberty secretion of gonadotropins is enhanced and secretion of LH occurs with the same periodicity as the sleep cycles. Two groups of dwarfish are seen: the first lacks both GH secretion during sleep and the increase of gonadotropins at puberty. The second group exhibits GH, LH and FSH secretion patterns similar to normal children. Study of secretion patterns of GH, FSH and LH during sleep in children can document the degree of maturation of the hypothalamic pituitary hormonal system.

摘要

在正常儿童中,主要的生长激素释放始于第一个睡眠周期的非快速眼动睡眠期。青春期时,促性腺激素的分泌增强,促黄体生成素的分泌与睡眠周期具有相同的周期性。可观察到两类侏儒症患者:第一类在睡眠期间既缺乏生长激素分泌,在青春期也缺乏促性腺激素增加;第二类患者的生长激素、促黄体生成素和促卵泡生成素分泌模式与正常儿童相似。研究儿童睡眠期间生长激素、促卵泡生成素和促黄体生成素的分泌模式,可以记录下丘脑 - 垂体激素系统的成熟程度。

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