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足部含铁血黄素性纤维组织细胞性脂肪瘤性病变/肿瘤:磁共振成像与组织病理学

Haemosiderotic fibrohistiocytic lipomatous lesion/tumour of the foot: MRI and histopathology.

作者信息

West Andrew T, Toms Andoni P, Murphy Joseph, Sultan Mohammed

机构信息

Department of Radiology, Norfolk & Norwich University Hospital, Colney Lane, Norwich NR4 7UY, UK.

出版信息

Skeletal Radiol. 2008 Jan;37(1):71-4. doi: 10.1007/s00256-007-0397-0. Epub 2007 Oct 30.

Abstract

A 38-year-old woman presented in 2005 with a fatty swelling over the dorsum of her left foot and was subsequently referred to our institution following initial biopsy for further management. MRI was performed before and after surgery. This demonstrated an ill-defined lesion confined to the subcutaneous tissues on the dorsum of the foot with heterogeneous intermediate and high T1 and T2 signal suggesting a complex mixture of fat and fibrous elements. The lesion recurred following initial surgery in the lateral aspect of the hind foot and along the lateral aspect of the ankle. It demonstrated extremely high signal on T2 fat-saturated sequences along the fibrous elements of the lesion and concentrated in a layer just deep to the dermis, which was mirrored on post-contrast images. A histopathological diagnosis of haemosiderotic fibrohistiocytic lipomatous lesion/tumour (HFLL/T) was made. This is a recently described and rare entity that occurs typically in the subcutaneous tissues of the foot or ankle of middle-aged women. To our knowledge this is the first description of the imaging findings in this lesion.

摘要

一名38岁女性于2005年因左脚背出现脂肪性肿胀就诊,在接受初步活检后被转至我院进行进一步治疗。手术前后均进行了MRI检查。结果显示,足部背侧皮下组织有一个边界不清的病变,T1和T2信号呈不均匀的中等和高信号,提示脂肪和纤维成分的复杂混合。初次手术后,病变在后足外侧和踝关节外侧复发。在T2脂肪抑制序列上,病变的纤维成分显示极高信号,并集中在真皮深层的一层,在增强后图像上也有类似表现。组织病理学诊断为含铁血黄素性纤维组织细胞性脂肪瘤样病变/肿瘤(HFLL/T)。这是一种最近才被描述的罕见疾病,通常发生在中年女性的足部或踝关节皮下组织。据我们所知,这是对该病变影像学表现的首次描述。

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