原肌球蛋白同工型多样性的分子基础。
The molecular basis for tropomyosin isoform diversity.
作者信息
Lees-Miller J P, Helfman D M
机构信息
Cold Spring Harbor Laboratory, New York, NY 11724.
出版信息
Bioessays. 1991 Sep;13(9):429-37. doi: 10.1002/bies.950130902.
PMID:1796905
Abstract
The tropomyosins are a family of actin filament binding proteins. In multicellular animals, they exhibit extensive cell type specific isoform diversity. In this essay we discuss the genetic mechanisms by which this diversity is generated and its possible significance to cellular function.
摘要
原肌球蛋白是一类肌动蛋白丝结合蛋白。在多细胞动物中，它们表现出广泛的细胞类型特异性同工型多样性。在本文中，我们讨论了产生这种多样性的遗传机制及其对细胞功能的可能意义。
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