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美国与心血管代谢危险因素簇相关的生产力成本。

Productivity costs associated with cardiometabolic risk factor clusters in the United States.

作者信息

Sullivan Patrick W, Ghushchyan Vahram, Wyatt Holly R, Wu Eric Q, Hill James O

机构信息

University of Colorado at Denver and Health Sciences Center, Pharmaceutical Outcomes Research Program, School of Pharmacy, 4200 East Ninth Avenue, C238, Denver, CO 80262, USA.

出版信息

Value Health. 2007 Nov-Dec;10(6):443-50. doi: 10.1111/j.1524-4733.2007.00199.x.

Abstract

OBJECTIVE

Cardiometabolic risk factors such as overweight/obesity, hyperlipidemia, diabetes, and hypertension are prone to cluster together in the same individual and result in an elevated risk of cardiovascular disease and mortality. The purpose of this study was to examine and quantify the impact of cardiometabolic risk factor clusters independent of heart disease on productivity in a nationally representative sample of US adults.

METHODS

The current study estimated the impact of cardiometabolic risk factor clusters on missed work days and bed days, controlling for sociodemographic characteristics, comorbidity, and smoking status in a nationally representative, pooled 2000 and 2002 Medical Expenditure Panel Survey sample. Cardiometabolic risk factor clusters included BMI >or= 25 and two of the following three: diabetes, hyperlipidemia, and/or hypertension. All estimates were expressedin $US 2005. Sensitivity analyses were conducted to examine the impact of varying assumptions on the results.

RESULTS

After controlling for differences in sociodemographics, smoking and comorbidity, individuals with cardiometabolic risk factor clusters missed 179% more work days and spent 147% more days in bed (in addition to lost work days) than those without. Lost work days and bed days resulted in $17.3 billion annually in lost productivity attributable to cardiometabolic risk factor clusters in the United States. Sensitivity analyses resulted in a range of annual lost productivity costs from $3.2 to $23.1 billion.

CONCLUSIONS

Common cardiometabolic risk factor clusters have a significant deleterious impact on the US economy, resulting in $17.3 billion in lost productivity.

摘要

目的

超重/肥胖、高脂血症、糖尿病和高血压等心脏代谢危险因素易于在同一个体中聚集在一起,导致心血管疾病和死亡风险升高。本研究的目的是在美国成年人的全国代表性样本中,检验并量化独立于心脏病的心脏代谢危险因素聚集对生产力的影响。

方法

本研究在2000年和2002年全国代表性的医疗支出小组调查合并样本中,估计心脏代谢危险因素聚集对误工天数和卧床天数的影响,并对社会人口统计学特征、合并症和吸烟状况进行控制。心脏代谢危险因素聚集包括体重指数(BMI)≥25以及以下三项中的两项:糖尿病、高脂血症和/或高血压。所有估计值均以2005年美元表示。进行敏感性分析以检验不同假设对结果的影响。

结果

在控制了社会人口统计学、吸烟和合并症的差异后,有心脏代谢危险因素聚集的个体比没有这些因素的个体误工天数多179%,卧床天数(除误工天数外)多147%。在美国,误工天数和卧床天数导致每年因心脏代谢危险因素聚集而造成的生产力损失达173亿美元。敏感性分析得出的每年生产力损失成本范围为32亿至231亿美元。

结论

常见的心脏代谢危险因素聚集对美国经济有重大的有害影响,导致173亿美元的生产力损失。

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