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与丙烯酸N-乙烯基吡咯烷酮共聚物偶联的A组链球菌M蛋白多肽片段的免疫原性

Immunogenicity of a polypeptide fragment of the streptococcal group A M protein conjugated with an acrylic acid N-vinylpyrrolidone copolymer.

作者信息

Lyampert I M, Semenova E N, Puchkova N G, Nekrasov A V

机构信息

Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow.

出版信息

Biomed Sci. 1991;2(4):410-4.

PMID:1797145
Abstract

Immunization of animals with a polypeptide fragment of the streptococcal group A M protein (pep M) conjugated with a synthetic copolymer caused a significant increase in the titres of bactericidal type-specific antibodies. In some cases bactericidal antibodies to streptococci of other types were also induced.

摘要

用与合成共聚物偶联的A组链球菌M蛋白多肽片段(pep M)对动物进行免疫接种,可使杀菌型特异性抗体的滴度显著升高。在某些情况下,还可诱导出针对其他类型链球菌的杀菌抗体。

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