一名局限性前列腺癌患者发生的异时性非霍奇金淋巴瘤。
Metachronous non-Hodgkin's lymphoma in a patient with localized prostate cancer.
作者信息
Kalender Mehmet E, Sevinc Alper, Tutar Ediz, Buyukberber Suleyman, Camci Celalettin
机构信息
School of Medicine, Department of Medical Oncology, Gaziantep Oncology Hospital, Gaziantep University, Gaziantep, Turkey.
出版信息
Med Oncol. 2007;24(4):466-8. doi: 10.1007/s12032-007-0024-x. Epub 2007 May 17.
INTRODUCTION
A higher frequency of second malignancies is observed in patients with prostate cancer. We report a case of indolent non-Hodgkin's lymphoma diagnosed 2 years after prostate carcinoma.
CASE REPORT
A 65-year-old man with diagnosis of localized prostate adenocarcinoma was presented with fatigue 2 years after prostatectomy operation. Abdominal ultrasonography showed hepatomegaly and paraaortocaval, parailiac, and perivascular multiple lymph nodes. The complete blood count revealed anemia and thrombocytopenia. Bone marrow biopsy demonstrated small lymphocytic lymphoma.
CONCLUSION
Lymphoma should be suspected in cases with newly appeared adenopathy and/or cytopenias during follow-up. In patients with clinically organ-confined prostate cancer, indolent lymphoma should be in the differential diagnosis of newly appeared lymphadenopathy.
引言
前列腺癌患者中观察到第二原发性恶性肿瘤的发生率较高。我们报告一例在前列腺癌诊断2年后确诊的惰性非霍奇金淋巴瘤病例。
病例报告
一名65岁男性，诊断为局限性前列腺腺癌，在前列腺切除术后2年出现疲劳症状。腹部超声显示肝肿大以及主动脉腔静脉旁、髂旁和血管周围多发淋巴结。全血细胞计数显示贫血和血小板减少。骨髓活检证实为小淋巴细胞淋巴瘤。
结论
随访期间出现新发淋巴结病和/或血细胞减少的病例应怀疑淋巴瘤。对于临床器官局限型前列腺癌患者，惰性淋巴瘤应列入新发淋巴结病的鉴别诊断。
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