Spiegel Jeffrey H, Varvares Mark A
Department of Otolaryngology-Head and Neck, Boston University School of Medicine, Boston, Massachusetts.
Skull Base. 2007 May;17(3):197-203. doi: 10.1055/s-2007-977468.
In patients for whom aggressive disease processes have necessitated the surgical removal of the orbital contents, many reconstructive options are available to address the exenteration cavity. While cavity lining, such as with a skin graft, has been commonly employed, areas of bone injury or loss may still provide a pathway for bacteria to access the cranial vault. We suggest that complete obliteration of the cavity provides a protective barrier, which minimizes this risk.
A retrospective review of four patients with significant intracranial infectious complications following orbital exenteration. All patients were managed at a tertiary care academic medical center.
Three of the four patients developed large brain abscesses, and one was symptomatic with computed tomography (CT) evidence of epidural enhancement in areas of bony dehiscence in the orbital cavity. Overall, three of the patients had free-tissue transfer to obliterate the orbit, and two of these had no further infectious problems. In one patient, the flap pulled away from the superior orbit leading to infectious complications, which were successfully managed by obliterating the remaining area of the orbit with a temporoparietal fascia flap.
In light of the overall prognosis of patients requiring orbital exenteration, we believe that tissue obliteration of the cavity as an initial management strategy provides advantages that outweigh the increased surgical time and loss of socket visualization.
对于因侵袭性疾病过程而需要手术切除眶内容物的患者,有多种重建方法可用于处理眶内容物摘除后的腔隙。虽然常用皮片等进行腔隙衬里,但骨损伤或骨缺失区域仍可能为细菌进入颅腔提供途径。我们认为完全闭塞腔隙可提供一个保护屏障,将这种风险降至最低。
对4例眶内容物摘除术后发生严重颅内感染并发症的患者进行回顾性研究。所有患者均在一家三级医疗学术中心接受治疗。
4例患者中有3例发生了巨大脑脓肿,1例患者经计算机断层扫描(CT)显示眶腔骨质缺损区域有硬膜强化并有症状。总体而言,3例患者采用游离组织移植来闭塞眼眶,其中2例未再出现感染问题。1例患者的皮瓣从眶上缘脱离,导致感染并发症,通过用颞顶筋膜瓣闭塞眼眶剩余区域成功处理。
鉴于需要进行眶内容物摘除的患者的总体预后,我们认为将腔隙组织闭塞作为初始治疗策略具有诸多优势,其优势超过了手术时间延长和眼窝可视化丧失的弊端。