Mambelli Emanuele, Mancini Elena, Santoro Antonio
Nephrology, Dialysis and Hypertension Unit, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Nephron Clin Pract. 2007;107(4):c170-6. doi: 10.1159/000110677. Epub 2007 Nov 1.
As symptomatic intradialytic hypotension in the hemodialysis (HD) patient is often a sudden event whose onset cannot be predicted by means of extemporary measures, continuous blood pressure (BP) measurement would be far more useful. We tested a new continuous noninvasive BP monitoring system, Harmonized Alert Sensing Technology (HASTE), which, by means of the analysis of the finger pulse wave, obtained from an O2 sensor, estimates a beat-to-beat systolic pressure value (Esys) and supplies a continuous read-out. The study aim sought to verify the reliability of this non-invasive instrument in continuously providing systolic pressure values during HD.
We studied 18 patients during HD treatment, initially comparing the Esys with the invasive blood pressure measurement (SYS). Subsequently, the Esys derived from the O2 sensor in the arm with the shunt (S) and the arm without (N), respectively, were both compared with the cuff measurement.
The mean difference between SYS and Esys was 0.7 +/- 13.3 mm Hg (p < 0.01; r = 0.80). There was a mean difference of 0.2 +/- 21.9 mm Hg (p = NS; r = 0.67) between Esys(N) and Esys(S). The correlation was not statistically significant even between Esys(N) or Esys(S) versus the cuff measurement, respectively. Patient movement compromised the accuracy of the estimations made using the O2 sensor in the non-fistula arm.
A good correlation between the data estimated by HASTE compared with invasive BP suggests that the instrument may prove useful for continuously monitoring the blood pressure trends during the dynamic hemodialysis situation. However, its sensibility needs to be improved in order to be used indifferently in both arms with a view to achieving real intradialytic hypotension prevention.
血液透析(HD)患者的症状性透析中低血压通常是突发情况,无法通过临时措施预测其发作,因此连续血压(BP)测量会更有用。我们测试了一种新的连续无创血压监测系统,即协调警报传感技术(HASTE),该系统通过分析从氧气传感器获取的手指脉搏波,估算逐搏收缩压值(Esys)并提供连续读数。本研究旨在验证该无创仪器在HD期间连续提供收缩压值的可靠性。
我们对18例HD治疗患者进行了研究,首先将Esys与有创血压测量值(SYS)进行比较。随后,分别将来自有分流(S)和无分流(N)手臂的氧气传感器得出的Esys与袖带测量值进行比较。
SYS与Esys之间的平均差值为0.7±13.3 mmHg(p<0.01;r = 0.80)。Esys(N)与Esys(S)之间的平均差值为0.2±21.9 mmHg(p =无统计学意义;r = 0.67)。Esys(N)或Esys(S)与袖带测量值之间的相关性也均无统计学意义。患者的活动影响了使用无瘘手臂上的氧气传感器进行估算的准确性。
与有创血压相比,HASTE估算的数据之间具有良好的相关性,这表明该仪器可能有助于在动态血液透析过程中连续监测血压趋势。然而,为了在双臂中均可无差别使用以真正预防透析中低血压,其灵敏度需要提高。