肺叶切除术后运动能力和肺功能的长期恢复

Long-term recovery of exercise capacity and pulmonary function after lobectomy.

作者信息

Nagamatsu Yoshinori, Maeshiro Kanetaka, Kimura Norman Y, Nishi Tatsuya, Shima Ichirou, Yamana Hideaki, Shirouzu Kazuo

机构信息

Department of Surgery, National Hospital Organization Omuta National Hospital, Ohmuta Fukuoka, Japan.

出版信息

J Thorac Cardiovasc Surg. 2007 Nov;134(5):1273-8. doi: 10.1016/j.jtcvs.2007.06.025.

DOI:10.1016/j.jtcvs.2007.06.025

PMID:17976462

Abstract

OBJECTIVE

The objective of the present study was to perform longitudinal objective evaluations of recovery of exercise capacity based on expired gas analysis during exercise testing up to 1 year after pulmonary resection.

METHODS

The study included 18 patients who underwent lobectomy. Expired gas analysis during exercise testing was conducted 1 week before surgery and 2 weeks, 1 month, 3 months, 6 months, and 1 year after surgery. The parameters studied included maximum exercise capacity based on expired gas analysis during exercise testing (maximum oxygen uptake per minute per square meter of body surface area) and assessment of moderate exercise capacity (anaerobic threshold per square meter of body surface area). The changes in postoperative data relative to the preoperative values (baseline) were assessed, including the percent changes from baseline data, which were arbitrarily given a value of 100.

RESULTS

Maximum oxygen uptake per minute per square meter of body surface area decreased significantly to 78.6% +/- 14.2% of the baseline value at 2 weeks after surgery and was 80.3% +/- 12.7%, 90.9% +/- 15.9%, 90% +/- 19.7%, and 97% +/- 4.8% of the baseline value at 1, 3, and 6 months, and 1 year, respectively. Anaerobic threshold per square meter of body surface area reached 91.1% +/- 17.5% of the baseline value even 2 weeks after surgery and was 87.1% +/- 17.3%, 97.5% +/- 28.0%, 84.3% +/- 13.2%, and 104% +/- 16.2% of the baseline value at 1, 3, and 6 months, and 1 year, respectively.

CONCLUSION

The extent of recovery of exercise capacity at 1 year after surgery was approximately 95%. Furthermore, the anaerobic threshold per square meter of body surface area was restored to the preoperative level by 1 year after surgery.

摘要

目的

本研究的目的是在肺切除术后长达1年的运动测试期间，基于呼出气体分析对运动能力的恢复进行纵向客观评估。

方法

该研究纳入了18例行肺叶切除术的患者。在手术前1周以及手术后2周、1个月、3个月、6个月和1年进行运动测试期间的呼出气体分析。研究的参数包括基于运动测试期间呼出气体分析的最大运动能力（每平方米体表面积每分钟的最大摄氧量）和中度运动能力评估（每平方米体表面积的无氧阈值）。评估术后数据相对于术前值（基线）的变化，包括相对于基线数据的百分比变化，基线数据被任意赋予值100。

结果

每平方米体表面积每分钟的最大摄氧量在术后2周时显著下降至基线值的78.6%±14.2%，在术后1个月、3个月、6个月和1年时分别为基线值的80.3%±12.7%、90.9%±15.9%、90%±19.7%和97%±4.8%。每平方米体表面积的无氧阈值即使在术后2周时也达到基线值的91.1%±17.5%，在术后1个月、3个月、6个月和1年时分别为基线值的87.1%±17.3%、97.5%±28.0%、84.3%±13.2%和104%±16.2%。