Savin M, Ramić Z, Djukanović Lj
Srp Arh Celok Lek. 1994 May-Jun;122(5-6):142-5.
Proliferative response of peripheral blood lymphocytes in patients with chronic renal allograft insufficiency was due to aetiological deterioration factors. The highest values of sponntaneous lymphocyte blastogenesis were found in chronic rejection of renal allografts, but on the similar level detected during acute renal rejection attacks. Significant raise of proliferative response was absent in cyclosporine nephropathy, as well as in patients with excellent renal allograft function, maintained on proliferative healthy control levels.
慢性肾移植功能不全患者外周血淋巴细胞的增殖反应归因于病因学恶化因素。自发淋巴细胞母细胞生成的最高值见于肾移植的慢性排斥反应,但与急性肾移植排斥发作期间检测到的水平相似。环孢素肾病患者以及肾移植功能良好并维持在健康增殖对照水平的患者,其增殖反应没有显著升高。