Kang Sungsoo, Yang Sung-Jin, Kim Sangsoo, Bhak Jong
KOBIC (Korean BioInformation Center), KRIBB, Daejeon 305-806 and Soongsil University, 1-1 Sangdo-dong, Dongjak-gu, Seoul 156-743, Korea.
Bioinformatics. 2007 Nov 15;23(22):3088-90. doi: 10.1093/bioinformatics/btm512. Epub 2007 Oct 31.
CONSORF is a fully automatic high-accuracy identification system that provides consensus prokaryotic CDS information. It first predicts the CDSs supported by consensus alignments. The alignments are derived from multiple genome-to-proteome comparisons with other prokaryotes using the FASTX program. Then, it fills the empty genomic regions with the CDSs supported by consensus ab initio predictions. From those consensus results, CONSORF provides prediction reliability scores, predicted frame-shifts, alternative start sites and best pair-wise match information against other prokaryotes. These results are easily accessed from a website.
CONSORF是一个提供一致性原核生物编码序列(CDS)信息的全自动高精度识别系统。它首先预测由一致性比对支持的CDS。这些比对来自使用FASTX程序与其他原核生物进行的多个基因组到蛋白质组的比较。然后,它用从头开始预测的一致性支持的CDS填充空白基因组区域。根据这些一致性结果,CONSORF提供预测可靠性得分、预测的移码、替代起始位点以及与其他原核生物的最佳成对匹配信息。这些结果可以很容易地从一个网站获取。