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成人氩离子凝固术与冷剥离扁桃体切除术的临床前瞻性随机研究

Argon plasma coagulation versus cold dissection tonsillectomy in adults: a clinical prospective randomized study.

作者信息

Ferri Emanuele, Armato Enrico, Capuzzo Paolo

机构信息

Department of Otorhinolaryngology, Hospital of Dolo (Venice), Italy.

出版信息

Am J Otolaryngol. 2007 Nov-Dec;28(6):384-7. doi: 10.1016/j.amjoto.2006.11.007.

Abstract

PURPOSE

Argon plasma coagulation (APC) is a new surgical procedure based on a conductive plasma of ionized argon between an activating electrode and a tissue surface. It is a good alternative for tonsillectomy because of its effective hemostasis and limited penetration depth of the coagulation beam. The aim of this prospective, randomized trial was to evaluate operative time, intraoperative bleeding, and postoperative morbidity of the "hot" APC tonsillectomy as with regard to with a traditional "cold" dissection tonsillectomy in adults.

MATERIALS AND METHODS

Two hundred twenty six adult patients (age, >18 years) were randomized into 2 groups: TA (tonsillectomy with APC, n = 113) and TB (conventional tonsillectomy, n = 113). The outcome measures were (1) operative time; (2) intraoperative blood loss; (3) postoperative pain (evaluated using a Visual Analogue Scale with a range score 0-10 on postoperative days 1, 3, 5, 8, and 15); and (4) postoperative primary and secondary hemorrhage. Statistical analysis was carried out using the Student t test.

RESULTS

In the TA group, the mean duration of operative time and the intraoperative blood loss were significantly reduced (P < .001). There was no statistically significant difference between 2 groups in the intensity of postoperative pain and the incidence of postoperative hemorrhage (P > .05).

CONCLUSIONS

Tonsillectomy with APC is a safe technique and offers an innovative procedure as with regard to the conventional cold dissection. It significantly reduces the operative time and the intraoperative blood loss without increasing the postoperative morbidity.

摘要

目的

氩等离子体凝固术(APC)是一种基于激活电极与组织表面之间的电离氩导电等离子体的新型外科手术。由于其有效的止血作用和凝固束有限的穿透深度,它是扁桃体切除术的一种良好替代方法。这项前瞻性随机试验的目的是评估成人“热”APC扁桃体切除术与传统“冷”剥离扁桃体切除术相比的手术时间、术中出血情况及术后发病率。

材料与方法

226例成年患者(年龄>18岁)被随机分为两组:TA组(APC扁桃体切除术,n = 113)和TB组(传统扁桃体切除术,n = 113)。观察指标包括:(1)手术时间;(2)术中失血量;(3)术后疼痛(在术后第1、3、5、8和15天使用视觉模拟评分法评估,评分范围为0 - 10分);(4)术后原发性和继发性出血。采用Student t检验进行统计学分析。

结果

TA组的平均手术时间和术中失血量显著减少(P <.001)。两组在术后疼痛强度和术后出血发生率方面无统计学显著差异(P >.05)。

结论

APC扁桃体切除术是一种安全的技术,相对于传统的冷剥离术提供了一种创新的术式。它显著缩短了手术时间和术中失血量,且不增加术后发病率。

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