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用于黑色素瘤早期检测的色素沉着病变诊所:初步结果。

Pigmented lesions clinic for early detection of melanoma: preliminary results.

作者信息

Nathansohn Nir, Orenstein Arie, Trau Henri, Liran Alon, Schachter Jacob

机构信息

Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Isr Med Assoc J. 2007 Oct;9(10):708-12.

Abstract

BACKGROUND

Early detection of malignant melanoma of the skin is the most important factor in patient survival. Naked-eye diagnostic sensitivity and specificity are low. Patients with multiple nevi are at high risk to develop melanomas and the clinical follow-up of such patients is difficult, resulting in missed melanomas on the one hand and unnecessary biopsies on the other.

OBJECTIVES

To describe the set-up of a special clinic aimed at early detection of melanoma and follow-up of high risk patients and preliminary results from 20 months of operation.

METHODS

We established a pigmented lesions clinic based on a digital photography studio enabling documentation and comparison over time of full body photography and dermoscopy.

RESULTS

In the first 20 months of work, 895 patients were seen, 206 of them for follow-up visits. A total of 29,254 photos were taken. Altogether, 236 lesions were suspicious (either clinically or dermoscopically) and the patients were advised to excise them. Seven melanomas were found in this initial examination (which did not include long-term follow-up).

CONCLUSIONS

With multimode photographic cutaneous surveillance, early detection of melanoma in high risk patients has been reported. Our clinic utilizes the same techniques and diagnostic algorithm as other leading clinics throughout the world, thus enabling us to deliver better follow-up for those patients.

摘要

背景

皮肤恶性黑色素瘤的早期检测是影响患者生存的最重要因素。肉眼诊断的敏感性和特异性较低。患有多发性痣的患者发生黑色素瘤的风险很高,对此类患者进行临床随访很困难,一方面会导致黑色素瘤漏诊,另一方面会导致不必要的活检。

目的

描述一家旨在早期检测黑色素瘤并对高危患者进行随访的专科诊所的设立情况以及运营20个月的初步结果。

方法

我们基于一个数码摄影工作室建立了一个色素沉着病变诊所,能够对全身摄影和皮肤镜检查进行记录并随时间进行比较。

结果

在工作的前20个月里,共接待了895名患者,其中206名进行了随访。总共拍摄了29254张照片。共有236个病变可疑(临床或皮肤镜检查方面),并建议患者将其切除。在这次初步检查(不包括长期随访)中发现了7例黑色素瘤。

结论

通过多模式皮肤摄影监测,已有报道称可在高危患者中早期检测出黑色素瘤。我们的诊所采用了与世界其他领先诊所相同的技术和诊断算法,从而能够为这些患者提供更好的随访服务。

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