Hodgins S, Cree A, Alderton J, Mak T
Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London, UK.
Psychol Med. 2008 Jul;38(7):975-87. doi: 10.1017/S0033291707002164. Epub 2007 Nov 8.
Conduct disorder (CD) prior to age 15 has been associated with an increased risk of aggressive behaviour and crime among men with schizophrenia. The present study aimed to replicate and extend this finding in a clinical sample of severely mentally ill men and women.
We examined a cohort of in-patients with severe mental illness in one mental health trust. A total of 205 men and women participated, average age 38.5 years. CD was diagnosed using a structured diagnostic tool. Alcohol and illicit drug use, aggressive behaviour and victimization were self-reported. Information on convictions was extracted from official criminal records. Analyses controlled for age and sex.
CD prior to age 15 was associated with an increased risk of assault over the lifespan [odds ratio (OR) 3.98, 95% confidence interval (CI) 1.87-8.44)], aggressive behaviour in the 6 months prior to interview (OR 2.66, 95% CI 1.24-5.68), and convictions for violent crimes (OR 3.19, 95% CI 1.46-6.97) after controlling for alcohol and illicit drug use. The number of CD symptoms present prior to age 15 significantly increased the risk of serious assaults over the lifespan, aggressive behaviour in the past 6 months, and violent crime after controlling for alcohol and illicit drug use.
Men and women with severe mental illness who have a history of CD by mid-adolescence are at increased risk for aggressive behaviour and violent crime. These patients are easily identifiable and may benefit from learning-based treatments aimed at reducing antisocial behaviour. Longitudinal, prospective investigations are needed to understand why CD is more common among people with than without schizophrenia.
15岁之前的品行障碍(CD)与精神分裂症男性的攻击行为和犯罪风险增加有关。本研究旨在在重度精神疾病男性和女性的临床样本中重复并扩展这一发现。
我们对一个精神卫生信托机构中的一组重度精神疾病住院患者进行了检查。共有205名男性和女性参与,平均年龄38.5岁。使用结构化诊断工具诊断品行障碍。酒精和非法药物使用、攻击行为和受害情况通过自我报告获取。定罪信息从官方犯罪记录中提取。分析对年龄和性别进行了控制。
15岁之前的品行障碍与终生攻击风险增加有关[优势比(OR)3.98,95%置信区间(CI)1.87 - 8.44],在访谈前6个月的攻击行为(OR 2.66,95% CI 1.24 - 5.68),以及在控制了酒精和非法药物使用后暴力犯罪的定罪(OR 3.19,95% CI 1.46 - 6.97)。15岁之前出现的品行障碍症状数量在控制了酒精和非法药物使用后显著增加了终生严重攻击、过去6个月攻击行为和暴力犯罪的风险。
青少年中期有品行障碍病史的重度精神疾病男性和女性攻击行为和暴力犯罪风险增加。这些患者易于识别,可能受益于旨在减少反社会行为的基于学习的治疗。需要进行纵向、前瞻性调查以了解为什么品行障碍在精神分裂症患者中比非精神分裂症患者中更常见。