Hansen G, Drablos P A, Steinert R
Acta Anaesthesiol Scand. 1977;21(3):211-5. doi: 10.1111/j.1399-6576.1977.tb01211.x.
Forty patients who underwent elective cholecystectomy were examined preoperatively and during the first postoperative week by physical examination, measurement of FVC and FEV1, arterial pH and blood gas analyses, and chest x-ray. Postoperative pulmonary complications (p.p.c.) were detected in 30 (75%) of the patients. Simple auscultation was the most sensitive tool in discovering p.p.c., but 18 of the 30 patients with complications also had a pathological chest x-ray. Obesity, smoking postoperative naso-gastric tube and postoperative wound infection were predisposing factors for p.p.c. Six patients with preoperative pulmonary disease all had a progress in their lung pathology. There was no definite relationship of duration of anaesthesia or drainage of the abdominal wound to development of p.p.c. The patients with p.p.c. showed a deeper and more prolonged fall in Pao2 postoperatively than the normal group. None of the normals showed an arterial Po2 below 70 mmHg in the postoperative course, while 63% of the p.p.c. group did. FVC and FEV1 showed marked reductions from preoperative values on the first postoperative day, and then gradually increased to near preoperative values after 1 week. Arterial pH and Pco2 showed no definite changes during the postoperative course.
对40例行择期胆囊切除术的患者在术前及术后第一周进行了体格检查、用力肺活量(FVC)和第一秒用力呼气量(FEV1)测量、动脉血pH值及血气分析以及胸部X线检查。30例(75%)患者发生了术后肺部并发症(PPC)。单纯听诊是发现PPC最敏感的手段,但30例有并发症的患者中有18例胸部X线检查也有异常。肥胖、吸烟、术后鼻胃管留置及术后伤口感染是PPC的诱发因素。6例术前有肺部疾病的患者肺部病变均有进展。麻醉持续时间或腹部伤口引流与PPC的发生无明确关系。发生PPC的患者术后动脉血氧分压(Pao2)下降比正常组更深、更持久。正常组术后过程中无一例动脉血氧分压低于70 mmHg,而PPC组有63%低于该值。FVC和FEV1在术后第一天较术前值显著降低,然后在1周后逐渐升至接近术前值。术后过程中动脉血pH值和二氧化碳分压(Pco2)无明确变化。