Absy M M
Renal Unit, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Am J Nephrol. 1991;11(4):301-4. doi: 10.1159/000168326.
Two case histories of patients with end-stage renal disease subsequently found to have primary hyperoxaluria are reported. In the setting of renal failure, the diagnosis is both difficult, due to diminished oxalate excretion, and important, because of frequent graft loss due to oxalate deposition after renal transplantation. The diagnosis was obtained by renal and bone biopsies. Plasma oxalate levels were normal in one patient and the other patient presented with extensive cystic bone lesions. Primary hyperoxaluria should be considered whenever nephrocalcinosis and/or nephrolithiasis are associated with end-stage renal disease.
报告了两例终末期肾病患者随后被发现患有原发性高草酸尿症的病例。在肾衰竭的情况下，由于草酸盐排泄减少，诊断既困难，又很重要，因为肾移植后因草酸盐沉积导致移植肾频繁丢失。诊断是通过肾活检和骨活检得出的。一名患者的血浆草酸盐水平正常，另一名患者出现广泛的囊性骨病变。每当肾钙质沉着症和/或肾结石与终末期肾病相关时，都应考虑原发性高草酸尿症。
