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Replacing damaged myocardium.

作者信息

Potapova Irina A, Doronin Sergey V, Kelly Damon J, Rosen Amy B, Schuldt Adam J T, Lu Zhongju, Guo Yuanjian, Kochupura Paul V, Robinson Richard B, Rosen Michael R, Brink Peter R, Gaudette Glenn R, Cohen Ira S

机构信息

Department of Physiology and Biophysics, Stony Brook University, Stonybrook, NY 11794-8661, USA.

出版信息

J Electrocardiol. 2007 Nov-Dec;40(6 Suppl):S199-201. doi: 10.1016/j.jelectrocard.2007.05.025.

Abstract

Heart failure survival after diagnosis has barely changed for more than half a century. Recently, investigation has focused on differentiation of stem cells in vitro and their delivery for use in vivo as replacement cardiac contractile elements. Here we report preliminary results using mesenchymal stem cells partially differentiated to a cardiac lineage in vitro. When delivered to the canine heart on an extracellular matrix patch to replace a full-thickness ventricular defect in vivo, they improve regional mechanical function. The delivered cells were also tracked, and some became myocytes with mature sarcomeres.

摘要

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Replacing damaged myocardium.
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本文引用的文献

1
A Caveat Emptor for myocardial regeneration: mechanical without electrical recovery will not suffice.
J Mol Cell Cardiol. 2007 Feb;42(2):285-8. doi: 10.1016/j.yjmcc.2006.11.001. Epub 2006 Dec 28.
2
Theoretical impact of the injection of material into the myocardium: a finite element model simulation.
Circulation. 2006 Dec 12;114(24):2627-35. doi: 10.1161/CIRCULATIONAHA.106.657270. Epub 2006 Nov 27.
3
Stem cell therapy enhances electrical viability in myocardial infarction.
J Mol Cell Cardiol. 2007 Feb;42(2):304-14. doi: 10.1016/j.yjmcc.2006.09.011. Epub 2006 Oct 27.
4
Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.
N Engl J Med. 2006 Sep 21;355(12):1210-21. doi: 10.1056/NEJMoa060186.
5
Skeletal myoblast transplantation in ischemic heart failure: long-term follow-up of the first phase I cohort of patients.
Circulation. 2006 Jul 4;114(1 Suppl):I108-13. doi: 10.1161/CIRCULATIONAHA.105.000521.
6
Regeneration gaps: observations on stem cells and cardiac repair.
J Am Coll Cardiol. 2006 May 2;47(9):1777-85. doi: 10.1016/j.jacc.2006.02.002. Epub 2006 Apr 17.
7
Accuracy and reproducibility of a subpixel extended phase correlation method to determine micron level displacements in the heart.
Med Eng Phys. 2007 Jan;29(1):154-62. doi: 10.1016/j.medengphy.2006.01.001. Epub 2006 Mar 13.
9
Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function.
Circulation. 2005 Aug 30;112(9 Suppl):I144-9. doi: 10.1161/CIRCULATIONAHA.104.524355.

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