Ryb Gabriel E, Dischinger Patricia C, Kufera Joseph A, Burch Cynthia A
The Charles McC. Mathias, Jr. National Study Center for Trauma and EMS, University of Maryland, Baltimore, Maryland 21201, USA.
J Trauma. 2007 Nov;63(5):1000-5. doi: 10.1097/TA.0b013e31815885c8.
To measure the combined contribution of change in velocity (Deltav), principal direction of force (PDOF), and restraint use on mortality after vehicular trauma.
The Crash Injury Research and Engineering Network population includes patients <8 years old with one injury with an Abbreviated Injury Scale score >or=3 or with two injuries with an Abbreviated Injury Scale score >or=2, who were occupants of a vehicle. Patients 15 years or younger; in rear collisions; back seat occupants; in crashes with Deltav >80 km/h, unknown Deltav, or unknown PDOF; or in vehicles without airbags were excluded. Mortality was analyzed in relation to Deltav (km/h), restraint use, and PDOF using chi2. Multiple logistic regression models were built, including possible confounders (body mass index, age, gender) and interactions were explored. An [alpha] = 0.05 was used for all statistics.
A total of 1,261 cases were included. Mortality was higher for unrestrained than for restrained patients (17% vs. 9%) and was higher for lateral than for frontal impact patients (17% vs. 11%). Higher mortality rates were also observed for Deltav 40-80 km/h than for Deltav <40 km/h (17% vs. 9%). Multiple logistic regression findings, after adjusting for age, gender, and body mass index, revealed significant effects of lateral PDOF (odds ratio [OR] 3.06 [2.03-4.61]), unrestrained status (OR 2.95 [2.01-4.38]), and Deltav 40-80 km/h (OR 3.65 [2.44-5.44]). Effect modification was found between PDOF and Deltav.
A Deltav 40 km/h to 80 km/h, lack of restraint use, and lateral impact significantly affects mortality. A synergistic effect was found between Deltav 40-80 km/h and lateral PDOF.
测量速度变化(Δv)、主要受力方向(PDOF)和使用约束装置对车辆创伤后死亡率的综合影响。
碰撞损伤研究与工程网络人群包括年龄小于8岁、有一处损伤且简略损伤量表评分≥3或有两处损伤且简略损伤量表评分≥2的车辆乘客。排除15岁及以下的患者;追尾碰撞中的患者;后座乘客;Δv>80 km/h、Δv未知或PDOF未知的碰撞事故中的患者;或未配备安全气囊车辆中的患者。使用卡方检验分析死亡率与Δv(km/h)、约束装置使用情况和PDOF之间的关系。建立了多元逻辑回归模型,纳入可能的混杂因素(体重指数、年龄、性别)并探讨了相互作用。所有统计分析均采用α=0.05。
共纳入1261例病例。未使用约束装置的患者死亡率高于使用约束装置的患者(17%对9%),侧面撞击患者的死亡率高于正面撞击患者(17%对11%)。Δv为40 - 80 km/h的患者死亡率也高于Δv<40 km/h的患者(17%对9%)。在调整年龄、性别和体重指数后,多元逻辑回归结果显示侧面PDOF(优势比[OR] 3.06 [2.03 - 4.61])、未使用约束装置状态(OR 2.95 [2.01 - 4.38])和Δv 40 - 80 km/h(OR 3.65 [2.44 - 5.44])有显著影响。发现PDOF和Δv之间存在效应修正。
Δv为40 km/h至80 km/h、未使用约束装置和侧面撞击显著影响死亡率。在Δv 40 - 80 km/h和侧面PDOF之间发现了协同效应。