Ctp1/CtIP与MRN复合物在同源重组的起始步骤中协同作用。
Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination.
作者信息
Takeda Shunichi, Nakamura Kyoko, Taniguchi Yoshihito, Paull Tanya T
机构信息
Department of Radiation Genetics, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo-ku, Kyoto 606-8501, Japan.
出版信息
Mol Cell. 2007 Nov 9;28(3):351-2. doi: 10.1016/j.molcel.2007.10.016.
PMID:17996697
Abstract
In a recent issue of Molecular Cell, Limbo et al. (2007) identify a new homologous recombination factor, Ctp1 in S. pombe, a homolog of Sae2/Com1 in S. cerevisiae and CtIP in mammals, that operates cooperatively with the MRN complex.
摘要
在最近一期的《分子细胞》杂志上，林博等人（2007年）在粟酒裂殖酵母中鉴定出一种新的同源重组因子Ctp1，它是酿酒酵母中Sae2/Com1以及哺乳动物中CtIP的同源物，能与MRN复合物协同发挥作用。
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