U2 小核核糖核蛋白：不仅适用于聚腺苷酸化 mRNA。

U2 snRNP: not just for poly(A) mRNAs.

作者信息

Marzluff William F

机构信息

Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

出版信息

Mol Cell. 2007 Nov 9;28(3):353-4. doi: 10.1016/j.molcel.2007.10.015.

DOI:10.1016/j.molcel.2007.10.015

PMID:17996698

Abstract

Polyadenylated mRNAs and replication-dependent histone mRNAs, which are not polyadenylated, share factors involved in 3' end formation. Friend et al. (2007) now report that the U2 snRNP, required for pre-mRNA splicing, is also required for histone mRNA 3' end formation.

摘要

多聚腺苷酸化的mRNA和非多聚腺苷酸化的复制依赖性组蛋白mRNA共享参与3'端形成的因子。Friend等人（2007年）现在报告说，前体mRNA剪接所需的U2 snRNP也是组蛋白mRNA 3'端形成所必需的。