抑制人白细胞弹性蛋白酶的人精浆顶体蛋白酶抑制剂（HUSI-II）变体。
Variants of human seminal acrosin inhibitor (HUSI-II) which inhibit human leukocyte elastase.
作者信息
Collins J, Taube W, Fink E, Möritz A, Fritz H
机构信息
GBF-Gesellschaft für Biotechnologische Forschung mbH, Braunschweig.
出版信息
Biomed Biochim Acta. 1991;50(4-6):683-5.
PMID:1801743
Abstract
A cDNA coding for human seminal inhibitor II was fused to the ompA-gene leader peptide for the expression in E. coli. The secreted protein is biologically active and correctly processed. Inhibitors of human leukocyte elastase were constructed by site-directed mutagenesis.
摘要
编码人精液抑制剂II的cDNA与ompA基因前导肽融合，以便在大肠杆菌中表达。分泌的蛋白质具有生物活性且加工正确。通过定点诱变构建了人白细胞弹性蛋白酶抑制剂。
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