Suzuki Shinichi
Division of Endocrine Surgery, Department of Surgery 2, Fukushima Medical University School of Medicine.
Nihon Rinsho. 2007 Nov;65(11):2079-86.
Anaplastic thyroid carcinoma (ATC) is most aggressive and poor prognosis among solid neoplasmas. Unfortunately, effective treatment for ATC is not established until now. We recommend new strategy for the treatment of ATC based on new UICC staging. Stage IV is recommended the surgical treatment, and Stage IVB, IVC are recommended systemic chemotherapy like as doxorubicin and cisplatin and external radiotherapy. If tumor become decreasing by these chemoradiation, salvage surgery will be preformed for complete resection. But survival period is not longer over 20 years, so the establishment of new treatment is desired.
间变性甲状腺癌(ATC)在实体瘤中侵袭性最强且预后最差。不幸的是,迄今为止尚未确立有效的ATC治疗方法。我们基于新的国际抗癌联盟(UICC)分期推荐ATC的新治疗策略。推荐IV期进行手术治疗,IVB期和IVC期推荐采用多柔比星和顺铂等全身化疗以及外照射放疗。如果肿瘤通过这些放化疗缩小,将进行挽救性手术以实现完全切除。但生存期不超过20年,因此需要确立新的治疗方法。