Martin Benjamin L, Kimelman David
Department of Biochemistry, University of Washington, Box 357350, Seattle, Washington 98195, USA.
Curr Biol. 2007 Nov 20;17(22):R975-7. doi: 10.1016/j.cub.2007.10.002.
Nodal signaling plays an essential role during the induction and patterning of vertebrate embryonic tissue types. In Xenopus and zebrafish, microRNAs regulate Nodal signaling, but surprisingly by very different mechanisms.
结节信号传导在脊椎动物胚胎组织类型的诱导和模式形成过程中起着至关重要的作用。在非洲爪蟾和斑马鱼中,微小RNA对结节信号传导进行调控,但令人惊讶的是,其调控机制截然不同。