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[脊柱和脊髓损伤后痉挛和疼痛综合征的临床表现及外科治疗的特点]

[The specific features of clinical manifestations and surgical treatment of spastic and pain syndromes after injury to the vertebral column and spinal cord].

作者信息

Dreval' O N, Chernykh I A, Baskov A V, Boev M V, Tsuladze I I, Lisitskiĭ I Iu

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2007 Jul-Sep(3):16-21; discussion 21-2.

Abstract

The purpose of the investigation was to study the clinical manifestations of spastic syndrome after injury to the vertebral column and spinal cord and to devise its surgical treatment policy. The investigation included 21 patients with significant spasticity or pain syndrome after severe injury to the vertebral column and spinal cord without any potential of motor recovery. All the patients were observed to have severe inferior paraplegia, cacesthesia following the radicular and conduction with total hypo- or anesthesia. Pain was rated, by using the visual analogue scale and the McGill questionnaire, spasticity was estimated by the Ashworth scale. The patients' motor activity was also evaluated. Bilateral rhizomyeolotomy of the dorsal root entry zone (DREZ) was performed in 10 patients with pain syndrome; posterior partial rhizidiotomy was made in 8 patients with spastic syndrome; 3 patients underwent epidural spinal cord stimulation. Groups with a preponderance of pain (47%) and spastic (53%) syndromes were identified. A clinically equal combination of spastic and pain components occurred rarely. Pain was maximally pronounced, neuropathic, metamerically radicular, in dermatomes from the level of injury. Leg spasticity was more marked and concurrent with contracture. The efficiency of lateral rhizomyelotomy of DREZ in the treatment of pain was 89% in the early period and 63% in the late (as long as 4 years) one. That of bilateral posterior partial rhizodiotomy in the treatment of spasticity was 75 and 75% in the early and late (as long as 2.5 years), respectively. Rhizomyelotomy of DREZ is a pathogenetically grounded and effective procedure when there is a preponderance of neuropathic metamerically radicular pain from the level of injury. Bilateral posterior partial rhizidiotomy is the method of choice in treating significant spasticity.

摘要

本研究旨在探讨脊柱和脊髓损伤后痉挛综合征的临床表现,并制定其外科治疗策略。该研究纳入了21例脊柱和脊髓严重损伤后出现明显痉挛或疼痛综合征且无任何运动恢复潜力的患者。所有患者均表现为严重的下肢截瘫、神经根性感觉异常及传导性完全减退或感觉缺失。采用视觉模拟量表和麦吉尔问卷对疼痛进行评分,用Ashworth量表评估痉挛程度。同时对患者的运动功能进行评估。对10例疼痛综合征患者实施双侧背根入髓区(DREZ)脊髓后根切断术;对8例痉挛综合征患者行双侧后根部分切断术;3例患者接受硬膜外脊髓刺激术。确定了以疼痛综合征为主(47%)和以痉挛综合征为主(53%)的两组。痉挛和疼痛成分在临床上同等程度出现的情况很少见。疼痛在损伤平面以下的皮节最为明显,呈神经性、节段性神经根性疼痛。腿部痉挛更明显且伴有挛缩。早期DREZ侧方脊髓后根切断术治疗疼痛的有效率为89%,后期(长达4年)为63%。双侧后根部分切断术治疗痉挛的早期和后期(长达2.5年)有效率分别为75%和75%。当损伤平面以下出现以神经性节段性神经根性疼痛为主时,DREZ脊髓后根切断术是一种基于发病机制且有效的手术方法。双侧后根部分切断术是治疗明显痉挛的首选方法。

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