Wenck Mary Anne, Van Sickle David, Drociuk Daniel, Belflower Amy, Youngblood Claire, Whisnant M David, Taylor Richard, Rudnick Veleta, Gibson James J
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Public Health Rep. 2007 Nov-Dec;122(6):784-92. doi: 10.1177/003335490712200610.
After a train derailment released approximately 60 tons of chlorine from a ruptured tanker car, a multiagency team performed a rapid assessment of the health impact to determine morbidity caused by the chlorine and evaluate the effect of this mass-casualty event on health-care facilities.
A case was defined as death or illness related to chlorine exposure. Investigators gathered information on exposure, treatment received, and outcome through patient questionnaires and medical record review. An exposure severity rating was assigned to each patient based on description of exposure, distance from derailment, and duration of exposure. A case involving death or hospitalization > or = 3 nights was classified as a severe medical outcome. Logistic regression was used to examine factors associated with severe medical outcomes.
Nine people died, 72 were hospitalized in nine hospitals, and 525 were examined as outpatients. Fifty-one people (8%) had a severe medical outcome. Of 263 emergency department visits within 24 hours of the incident, 146 (56%) were in Augusta, Georgia; at least 95 patients arrived at facilities in privately owned vehicles. Patients with moderate-to-extreme exposure were more likely to experience a severe medical outcome (relative risk: 15.2; 95% confidence interval 4.8, 47.8) than those with a lower rating.
The rapid investigation revealed significant morbidity and mortality associated with an accidental release of chlorine gas. Key findings that should be addressed during facility, community, state, and regional mass-casualty planning include self-transport of symptomatic people for medical care and impact on health-care facilities over a wide geographic area.
一列火车脱轨致使一辆破裂的油罐车泄漏了约60吨氯气后,一个多机构团队对健康影响进行了快速评估,以确定氯气导致的发病率,并评估这起大规模伤亡事件对医疗设施的影响。
将与氯气暴露相关的死亡或疾病定义为病例。调查人员通过患者问卷和病历审查收集了有关暴露情况、接受的治疗及结果的信息。根据暴露描述、与脱轨地点的距离和暴露持续时间,为每位患者指定了暴露严重程度等级。涉及死亡或住院≥3晚的病例被归类为严重医疗后果。采用逻辑回归分析与严重医疗后果相关的因素。
9人死亡,72人在9家医院住院,525人接受门诊检查。51人(8%)出现严重医疗后果。在事件发生后24小时内的263次急诊就诊中,146次(56%)发生在佐治亚州奥古斯塔;至少95名患者乘坐私家车前往医疗机构。与暴露等级较低的患者相比,中度至重度暴露的患者更有可能出现严重医疗后果(相对风险:15.2;95%置信区间4.8,47.8)。
快速调查显示,氯气意外泄漏导致了显著的发病率和死亡率。在机构、社区、州和地区大规模伤亡事件规划中应解决的关键发现包括有症状者自行前往就医以及对广泛地理区域内医疗设施的影响。