在伴有大的卵圆孔未闭（PFO）的受试者中，偏头痛伴先兆发作期间的扩散加权磁共振成像（Diffusion MRI）与诊断性微泡注射相关。

Diffusion MRI during migraine with aura attack associated with diagnostic microbubbles injection in subjects with large PFO.

作者信息

Dinia Lavinia, Roccatagliata Luca, Bonzano Laura, Finocchi Cinzia, Del Sette Massimo

机构信息

Department of Neurosciences, Ophthalmology and Genetics, University of Genova, Italy.

出版信息

Headache. 2007 Nov-Dec;47(10):1455-6. doi: 10.1111/j.1526-4610.2007.00948.x.

DOI:10.1111/j.1526-4610.2007.00948.x

PMID:18052957

Abstract

The relationship between migraine with aura and patent foramen ovale (PFO) is still debatable. We report 2 cases of migraine with aura attacks after diagnostic microbubble injection for contrast transcranial Doppler (cTCD), in subjects with large PFO. In one case MR images, including diffusion weighted imaging and apparent diffusion coefficient, performed during aura did not show any signal abnormality. Patients with migraine with aura may have an attack during cTCD, probably by a "non-ischemic" mechanism.

摘要

伴有先兆的偏头痛与卵圆孔未闭（PFO）之间的关系仍存在争议。我们报告了2例在诊断性微泡注射用于对比经颅多普勒（cTCD）后出现先兆偏头痛发作的病例，这些病例存在较大的卵圆孔未闭。在其中1例中，先兆发作期间进行的磁共振成像（包括弥散加权成像和表观扩散系数）未显示任何信号异常。伴有先兆的偏头痛患者在cTCD检查期间可能会发作，可能是通过一种“非缺血性”机制。