Tan S M, Teh H S, Mancer J F Kent, Poh W T
Department of Surgery, Changi General Hospital, Singapore.
Breast. 2008 Jun;17(3):252-7. doi: 10.1016/j.breast.2007.10.015. Epub 2007 Nov 28.
Ultrasound elastography using the extended combined auto-correlation method of tissue elasticity allows for real-time strain image visualisation using a free-hand probe with concurrent conventional B mode imaging. Four hundred and fifteen consecutive women with 550 breast lesions confirmed on B mode ultrasound were assessed with elastography using the elasticity score. There were 119 malignant and 431 benign lesions. The elastography sensitivity was 78.0%, specificity was 98.5% and overall accuracy was 93.8%. The median score for malignancy was 5 and that for benign lesions was 2. There was good correlation with B mode BIRADS category. 98.6% of lesions with an elasticity score of 2 or below (95%CI=96.8-99.4) were benign. BIRADS 3 lesions with an elasticity score of 2 or below may be re-classified as BIRADS 2 lesions. We found that 15.3% of BIRADS 2 and 3 lesions with an elasticity score of 3 were malignant. Real-time ultrasound elastography is user-friendly with a high accuracy rate, thereby improving B mode ultrasound assessment.
使用组织弹性扩展联合自相关方法的超声弹性成像技术，能够通过手持探头在进行传统B模式成像的同时实现实时应变图像可视化。对415名经B模式超声确诊有550处乳腺病变的连续女性患者，采用弹性评分法进行弹性成像评估。其中有119处恶性病变和431处良性病变。弹性成像的敏感性为78.0%，特异性为98.5%，总体准确率为93.8%。恶性病变的中位评分为5分，良性病变的中位评分为2分。与B模式乳腺影像报告和数据系统（BIRADS）分类有良好的相关性。弹性评分为2分及以下的病变中，98.6%（95%置信区间=96.8 - 99.4）为良性。弹性评分为2分及以下的BIRADS 3类病变可重新分类为BIRADS 2类病变。我们发现，弹性评分为3分的BIRADS 2类和3类病变中有15.3%为恶性。实时超声弹性成像操作简便，准确率高，从而改善了B模式超声评估。
