Povoroznyuk V V, Dzerovich N I, Karasevskaya T A
Department of Clinical physiology and Pathology of Locomotor Apparatus, Institute of Gerontology AMS Ukraine, Kiev, Ukraine.
Ann N Y Acad Sci. 2007 Nov;1119:243-52. doi: 10.1196/annals.1404.019.
We determined the bone mineral density (BMD) of normal Ukrainian female subjects and compared results with USA-European reference data. The research was conducted at the Ukrainian Scientific-Medical Centre for the Problems of Osteoporosis and included 353 women aged 20-79 years. Conventional BMD measurements of the spine (L1-L4 in the anterior-posterior position), proximal femur (neck, Ward's triangle, and trochanter regions), and radial shaft (33% site) were determined by dual-energy X-ray absorptiometry using a densitometer Prodigy. Age-related changes in BMD were similar in form to those of USA-European reference data. We found that the BMD values of spine for Ukrainian women of 50-59 years were lower than published values. Regression analyses showed that weight was a significant predictor of female spine and femur BMD for both the premenopausal and the postmenopausal decades. Age was a significant predictor of female spine BMD in the 50- to 79-year age group. The prevalence of osteoporosis and osteopenia for Ukrainian women was 11% at the femoral neck and 20% and 24% at the spine and radial shaft, respectively.
我们测定了乌克兰正常女性受试者的骨密度（BMD），并将结果与美国 - 欧洲参考数据进行比较。该研究在乌克兰骨质疏松问题科学医学中心进行，纳入了353名年龄在20 - 79岁的女性。使用骨密度仪Prodigy通过双能X线吸收法测定脊柱（前后位L1 - L4）、股骨近端（颈部、沃德三角区和转子区）以及桡骨干（33%位点）的传统骨密度。骨密度的年龄相关变化在形式上与美国 - 欧洲参考数据相似。我们发现，50 - 59岁乌克兰女性的脊柱骨密度值低于已发表的值。回归分析表明，体重是绝经前和绝经后数十年女性脊柱和股骨骨密度的重要预测指标。年龄是50至79岁年龄组女性脊柱骨密度的重要预测指标。乌克兰女性骨质疏松症和骨质减少症的患病率在股骨颈处为11%，在脊柱和桡骨干处分别为20%和24%。
