女性注射吸毒者的童年性虐待和身体虐待史、创伤后应激障碍、抑郁症及艾滋病病毒感染风险结果：一条潜在的中介途径。
Childhood sexual and physical abuse histories, PTSD, depression, and HIV risk outcomes in women injection drug users: a potential mediating pathway.
作者信息
Plotzker Rosalyn E, Metzger David S, Holmes William C
机构信息
Center for the Studies of Addiction, HIV Prevention Division, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, USA.
出版信息
Am J Addict. 2007 Nov-Dec;16(6):431-8. doi: 10.1080/10550490701643161.
We explored links between childhood sexual abuse (CSA), childhood physical abuse (CPA), posttraumatic stress disorder (PTSD)/depression, and women injection drug users' (IDUs') risk in 113 women recruited from two syringe exchange sites. More than half (56%) reported CSA, 68% CPA, 23% likely were depressed-only, and 53% likely had PTSD/depression. CSA was associated with sexual (p = 0.003) and drug risk (p = 0.05); CPA was not. CSA was associated with PTSD/depression (p = 0.03); PTSD/depression was associated with sexual (p < 0.01) and drug (p < 0.03) risk. After PTSD/depression adjustment, CSA was no longer associated with sexual or drug risk. These results suggest that women IDUs' CSA-to-risk path is mediated by PTSD/depression.
我们在从两个针头交换点招募的113名女性注射吸毒者中，探究了童年期性虐待（CSA）、童年期身体虐待（CPA）、创伤后应激障碍（PTSD）/抑郁症与女性注射吸毒者风险之间的联系。超过半数（56%）报告曾遭受CSA，68%报告曾遭受CPA，23%可能仅患有抑郁症，53%可能患有PTSD/抑郁症。CSA与性风险（p = 0.003）和毒品风险（p = 0.05）相关；CPA则不然。CSA与PTSD/抑郁症相关（p = 0.03）；PTSD/抑郁症与性风险（p < 0.01）和毒品风险（p < 0.03）相关。在对PTSD/抑郁症进行校正后，CSA与性风险或毒品风险不再相关。这些结果表明，女性注射吸毒者中CSA至风险的路径是由PTSD/抑郁症介导的。
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