Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML.
作者信息
Hasle H, Abrahamsson J, Arola M, Karow A, O'Marcaigh A, Reinhardt D, Webb D K H, van Wering E, Zeller B, Zwaan C M, Vyas P
出版信息
Leukemia. 2008 Jul;22(7):1428-30. doi: 10.1038/sj.leu.2405060. Epub 2007 Dec 6.