Andover Margaret S, Gibb Brandon E, Miller Ivan W
Psychosocial Research Program, Butler Hospital and Brown Medical School, Providence, RI 02906, USA.
Compr Psychiatry. 2008 Jan-Feb;49(1):6-12. doi: 10.1016/j.comppsych.2007.07.006. Epub 2007 Oct 24.
Little is known about the emergence of suicidal ideation among psychiatric inpatients with histories of no, single, or multiple suicide attempts. We investigated differences in time to reemergence of severe suicidal ideation among psychiatric patients as a function of their suicide attempt histories.
One hundred seventeen individuals meeting criteria for a major depressive disorder who were recently discharged from a psychiatric hospital and participating in a larger study of treatments for depression were included in the current study. Suicidal ideation, depressive symptoms, hopelessness, and depressogenic cognitions were assessed at baseline, and suicidal ideation was assessed at 3-, 6-, 12-, and 18-month follow-up, as well as inpatient readmission if applicable. Time to the reemergence of severe suicidal ideation was analyzed using survival analysis.
Twenty-two percent of our sample reported the occurrence of severe suicidal ideation over an 18-month period. Severe suicidal ideation emerged earlier among patients who had a history of prior suicide attempts than those who did not, but single and multiple suicide attempters did not differ significantly in time to severe suicidal ideation. Suicide attempt history remained a significant predictor of time to severe suicidal ideation when statistically controlling for hopelessness, depressive symptoms, depressogenic cognitions, and suicidal ideation at admission and initial treatment group assignment, especially between single attempters and nonattempters.
Although nearly a quarter of participants endorsed severe, clinically significant suicidal ideation within 18 months of discharge, those with suicide attempt histories reported the occurrence of severe suicidal ideation significantly earlier than those without suicide attempt histories.
对于既往无自杀企图、有单次自杀企图或有多次自杀企图的精神科住院患者中自杀意念的出现情况,我们了解甚少。我们调查了精神科患者中严重自杀意念再次出现的时间差异与他们自杀企图史之间的关系。
本研究纳入了117名符合重度抑郁症标准且近期从精神病院出院并参与一项更大规模抑郁症治疗研究的个体。在基线时评估自杀意念、抑郁症状、绝望感和抑郁性认知,并在3个月、6个月、12个月和18个月的随访时评估自杀意念,如有再次住院则在住院时评估。使用生存分析来分析严重自杀意念再次出现的时间。
我们样本中的22%报告在18个月内出现了严重自杀意念。有既往自杀企图史的患者比无自杀企图史的患者更早出现严重自杀意念,但单次自杀企图者和多次自杀企图者在出现严重自杀意念的时间上没有显著差异。在对绝望感、抑郁症状、抑郁性认知以及入院时的自杀意念和初始治疗组分配进行统计控制后,自杀企图史仍然是严重自杀意念出现时间的一个重要预测因素,尤其是在单次自杀企图者和无自杀企图者之间。
尽管近四分之一的参与者在出院后18个月内认可了严重的、具有临床意义的自杀意念,但有自杀企图史的患者报告出现严重自杀意念的时间明显早于无自杀企图史的患者。