Bonanno Clarissa, Dove Lorna
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA.
Semin Perinatol. 2007 Dec;31(6):348-53. doi: 10.1053/j.semperi.2007.09.004.
There have been great strides in transplant medicine over the past few decades, and hundreds of pregnancies have now been reported in liver transplant recipients. Information on pregnancy in transplant patients has been collected through case reports, retrospective center-specific studies, and voluntary registries. Overall, favorable pregnancy outcomes have been reported for these patients. Pregnancy complications, however, are more common in liver transplant recipients than in the general population. Accordingly, pregnancies in liver transplant recipients should be followed by a multidisciplinary team involving both maternal fetal medicine specialists and transplant physicians. This chapter outlines the available data on the maternal and obstetrical outcomes of pregnancies in liver transplant recipients, and will review guidelines for management of these high-risk pregnancies.
在过去几十年里,移植医学取得了巨大进展,目前已有数百例肝移植受者怀孕的报道。关于移植患者怀孕的信息是通过病例报告、特定中心的回顾性研究以及自愿登记系统收集的。总体而言,这些患者的妊娠结局良好。然而,肝移植受者的妊娠并发症比普通人群更为常见。因此,肝移植受者的妊娠应由包括母胎医学专家和移植医生在内的多学科团队进行随访。本章概述了肝移植受者妊娠的母体和产科结局的现有数据,并将回顾这些高危妊娠的管理指南。