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罗哌卡因用于开胸术后镇痛和呼吸功能的肋间镇痛与硬膜外镇痛比较

Interpleural versus epidural analgesia with ropivacaine for postthoracotomy pain and respiratory function.

作者信息

Yildirim Vedat, Akay Hakki Tankut, Bingol Hakan, Bolcal Cengiz, Oz Kursad, Kaya Erkan, Demirkilic Ufuk, Tatar Harun

机构信息

Department of Anesthesiology and Reanimation, Gülhane Military Medical Academy, Ankara, Turkey.

出版信息

J Clin Anesth. 2007 Nov;19(7):506-11. doi: 10.1016/j.jclinane.2007.04.005.

Abstract

STUDY OBJECTIVE

To evaluate the impact of interpleural analgesia (IP) on postthoracotomy pain and respiratory function as an alternative to thoracic epidural analgesia (TEA).

DESIGN

Prospective, randomized study.

SETTING

Tertiary-care military hospital.

PATIENTS

Sixty young patients scheduled for elective thoracic surgery (correction of aorta coarctation and patent ductus arteriosus).

INTERVENTIONS

Patients were randomized into two groups to receive either IP or TEA for postthoracotomy pain management.

MEASUREMENTS

Patients in the IP group (n = 30) had a catheter inserted between the parietal and visceral pleura by a surgeon, and 0.2% ropivacaine was given through this catheter. In the TEA group, ropivacaine was administered through a thoracic epidural catheter. The impact of both methods on pain control, respiratory function, and pulmonary complications was analyzed and compared.

MAIN RESULTS

The frequency of atelectasis and pleural effusion was also significantly high in the IP group (P < 0.01). Respiratory function and postoperative pain scores were better in the TEA group (P < 0.01). Arterial blood gas analysis on the fifth postoperative day was significantly better in the TEA group.

CONCLUSION

Thoracic epidural analgesia has more beneficial effects on respiratory function and postoperative pain after thoracotomy than does IP.

摘要

研究目的

评估胸膜间镇痛(IP)作为胸段硬膜外镇痛(TEA)的替代方法对开胸术后疼痛及呼吸功能的影响。

设计

前瞻性随机研究。

地点

三级护理军事医院。

患者

60例计划行择期胸外科手术(主动脉缩窄及动脉导管未闭矫治术)的年轻患者。

干预措施

将患者随机分为两组,分别接受IP或TEA用于开胸术后疼痛管理。

测量指标

IP组(n = 30)患者由外科医生在壁层胸膜与脏层胸膜之间插入导管,通过该导管给予0.2%罗哌卡因。TEA组通过胸段硬膜外导管给予罗哌卡因。分析并比较两种方法对疼痛控制、呼吸功能及肺部并发症的影响。

主要结果

IP组肺不张和胸腔积液的发生率也显著较高(P < 0.01)。TEA组的呼吸功能和术后疼痛评分更好(P < 0.01)。术后第5天TEA组的动脉血气分析结果明显更好。

结论

与IP相比,胸段硬膜外镇痛对开胸术后的呼吸功能和疼痛更有益。

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