Sanna C M, Corrias A, Congiu G, Dessì S, Versace R, Corda R
Istituto di Clinica Pediatrica, Università di Cagliari, Italia.
Pediatr Med Chir. 1991 Nov-Dec;13(6):645-7.
Anaerobic infections are quite rare in pediatric age, being that, they affect only neonates and immunodepressed patients. We think to be somewhat interesting to describe the case of our patient, a 9 year old boy, unaffected by any predisposing factor, came under our observation because of a severe respiratory distress. He showed evident clinical and radiological signs of pleural effusion in the right lung, together with a gas coil in the upper field and a left mediastinal shifting. A thoracentesis was then performed, giving rise to 600 ml of foul smelling purulent material; this procedure promptly improved his respiratory function. A permanent drainage trough the chest wall was set and an antibiotic therapy, based on the clinical picture and the character of the exudate, begun. In effect, the typical smell of the purulent material led us to suspect an anaerobic infection, and for this reason we employed the teicoplanin iv, a rarely used in the pediatric age drug. While blood cultures were negative for any organism, exudate cultures yielded Peptostreptococcus anaerobius; the last one resulted highly sensible following antibiogram to the previously chosen drug. The x-ray pattern and the rapid disappearing of the gas coil induced us to exclude further either congenital or acquired lung diseases. We conclude that, in absence of other proved sources of entry, the air presence in the pleural space was secondary to gas formation by the anaerobic micro-organism. The clinical course was very satisfactory allowing the patient to be dismissed on the 28th hospital day, with no need of further surgical therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
厌氧菌感染在儿童期相当罕见,仅影响新生儿和免疫功能低下的患者。我们认为描述我们这位患者的病例有点意思,这是一名9岁男孩,没有任何易感因素,因严重呼吸窘迫前来我们处就诊。他表现出右肺胸腔积液明显的临床和放射学征象,同时上叶有气体盘管和左纵隔移位。随后进行了胸腔穿刺,抽出600毫升有恶臭的脓性物质;该操作迅速改善了他的呼吸功能。通过胸壁设置了永久性引流,并根据临床症状和渗出液特征开始了抗生素治疗。实际上,脓性物质的典型气味使我们怀疑是厌氧菌感染,因此我们使用了替考拉宁静脉注射,这是一种在儿童期很少使用的药物。血培养未发现任何微生物生长,渗出液培养分离出厌氧消化链球菌;根据药敏试验,最后一种细菌对先前选用的药物高度敏感。X线表现以及气体盘管迅速消失使我们排除了先天性或后天性肺部疾病。我们得出结论,在没有其他已证实的感染源的情况下,胸腔内气体的存在是由厌氧微生物产气所致。临床过程非常令人满意,患者在住院第28天出院,无需进一步手术治疗。(摘要截短至250字)