Sanz Esponera Julián
An R Acad Nac Med (Madr). 2007;124(2):319-32; discussion 330-2.
Meningiomas are still defined as benignant tumours although 25% of those tumours will have local recurrance in the follow-up period. The WHO (2000) classification divides meningiomas in three goups: Grade 1 for conventional meningioma. Grade 2 for atypical meningioma and Grade 3 for Anaplastic meningioma. Specific histological variants of meningiomas have been included in grade 2 tumours. Clear cell, rabdoid and papillary meningiomas. We obtained 250 meningiomas from our files and we analyzed 30 inmunohistochemical markers. Several markers can be actually used as prognostic indicators in meningiomas and may allow a more individualized management of patients.
脑膜瘤仍被定义为良性肿瘤，尽管其中25%的肿瘤在随访期会出现局部复发。世界卫生组织（2000年）分类将脑膜瘤分为三组：传统型脑膜瘤为1级，非典型脑膜瘤为2级，间变性脑膜瘤为3级。脑膜瘤的特定组织学变异型已被纳入2级肿瘤，即透明细胞型、横纹肌样型和乳头状脑膜瘤。我们从档案中获取了250例脑膜瘤，并分析了30种免疫组化标志物。实际上，几种标志物可作为脑膜瘤的预后指标，可能有助于对患者进行更个体化的管理。
