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[血管性癫痫的临床流行病学研究]

[Clinical epidemiological study of vascular epilepsy].

作者信息

Ribacoba-Montero R, Pujols-Castillo Y, Vallina-García M I, Menéndez-González M, Salas-Puig J, de la Vega-Cerezales V

机构信息

Unidad de Neurología, Hospital Comarcal Alvarez Buylla, Mieres Asturias, España.

出版信息

Rev Neurol. 2007;45(12):719-24.

Abstract

INTRODUCTION

Little research has been conducted on vascular epilepsy (VE) in our environment, although some authors claim it accounts for 45% of all symptomatic epilepsies in persons over 60 year of age.

PATIENTS AND METHODS

We obtained a cross-sectional sample of the hospital admissions that took place in our health area between 1999 and 2005 using the diagnosis-related group coding system with numbers 14 (specific cerebrovascular disorders, except transient ischemic attacks and intracerebral haemorrhages) and 810 (intracerebral haemorrhages), and crossing them with an admission diagnosis of epileptic seizures or symptomatic status epilepticus. We recruited 101 patients who had been diagnosed with VE (taking into account only those who had seizures two weeks after the acute event). This represented 9.14% of all new cases of epilepsy over that period of time.

RESULTS

After rejecting patients who had had their stroke before 1999 and those for whom no accurate record of the event was available, we obtained an incidence of VE in ischaemic strokes of 6.5%, with a figure of 11.6% for haematomas. Status epilepticus was reported in 27.7% of cases. Early status epilepticus was associated with a mortality rate of 77.7%.

CONCLUSIONS

Although the incidence of VE is higher than in other series that have appeared in the literature, our sample is too small to be able to extract data concerning demographic characteristics. Nevertheless, its prevalence makes it an important health issue that increases the rate at which resources are used and adds further insecurity in the case of individuals who already suffer some degree of disability.

摘要

引言

在我们所处的环境中,对血管性癫痫(VE)的研究较少,尽管一些作者声称它占60岁以上人群所有症状性癫痫的45%。

患者与方法

我们使用诊断相关分组编码系统(编号14,特定脑血管疾病,不包括短暂性脑缺血发作和脑出血;以及编号810,脑出血),获取了1999年至2005年期间在我们健康区域住院的横断面样本,并将其与癫痫发作或症状性癫痫持续状态的入院诊断进行交叉分析。我们招募了101例被诊断为VE的患者(仅考虑急性事件两周后仍有发作的患者)。这占该时间段内所有癫痫新病例的9.14%。

结果

排除1999年之前发生中风的患者以及那些事件记录不准确的患者后,我们得出缺血性中风中VE的发生率为6.5%,血肿患者的发生率为11.6%。27.7%的病例报告有癫痫持续状态。早期癫痫持续状态的死亡率为77.7%。

结论

尽管VE的发生率高于文献中出现的其他系列研究,但我们的样本太小,无法提取有关人口统计学特征的数据。然而,其患病率使其成为一个重要的健康问题,增加了资源使用的速率,并给已经有一定程度残疾的个体带来更多不安全感。

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