Miller P L, Shifman M A, Kidd K K
Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510.
Proc Annu Symp Comput Appl Med Care. 1991:409-13.
We are building a database for the storage, retrieval, and graphical display of physical gene mapping data. To allow this information to be analyzed robustly, such a database must confront the inherent uncertainty of the data as a central design issue. The paper describes the overall database design, the types of gene mapping data which the system will contain, the types of uncertainty in the data, and certain of the design issues involved in allowing the database to handle uncertainty in a comprehensive fashion. Only if a full appreciation of uncertainty is built into the system from its inception will a physical gene mapping database be truly robust and successful.
我们正在构建一个用于存储、检索和以图形方式显示物理基因图谱数据的数据库。为了能够对这些信息进行可靠的分析,这样一个数据库必须将数据中固有的不确定性作为核心设计问题来面对。本文描述了数据库的整体设计、系统将包含的基因图谱数据类型、数据中的不确定性类型,以及让数据库以全面方式处理不确定性所涉及的某些设计问题。只有从一开始就在系统中充分认识到不确定性,物理基因图谱数据库才会真正强大且成功。