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[针刺不同穴位对胃动力异常大鼠双向调节作用的研究]

[Study on dual-directional regulation induced by acupuncture at different acupoints in the rat with motility abnormality of the stomach].

作者信息

Sun Guo-Jie, Wang Shu-Ju, Du Yan-Jun, Hu He-Ping, Wu Xu-Ping, Kong Li-Hong

机构信息

Hubei College of TCM, Wuhan 430061, China.

出版信息

Zhongguo Zhen Jiu. 2007 Nov;27(11):839-42.

Abstract

OBJECTIVE

To probe into the bidirectional regulation of acupuncture in the rat with motility abnormality of the stomach and the nerve mechanism.

METHODS

Adopting electrophysiological methods, the extracellular discharge signals of neuronic action in NTS were recorded with glass microelectrodes. The effects of acupuncture at "Zusanli" (ST 36), "Neiguan" (PC 6), "Zhongwan" (CV 12), "Qihai" (CV 6) on discharges of NTS neurons and intra-gastric pressure were observed in the rat at normal physiological state, and increase or reduction of gastric motility.

RESULTS

Acupuncture at "Zusanli" (ST 36), "Neiguan" (PC 6) could significantly promote gastric motility of the rat at normal status, increase or reduction of gastric motion, while acupuncture at "Zhongwan" (CV 12), "Qihai" (CV 6) could significantly inhibit gastric motion. And acupuncture at all the above acupoints could activate discharges of NTS neurons.

CONCLUSION

The bidirectional regulation effect of an acupoint does not certainly indicate that the same point has bidirectional regulation effect on an internal organs at different pathological states, while this may show synthetic action of different points which is a good regulation towards normal states and homeostasis.

摘要

目的

探讨针刺对胃动力异常大鼠的双向调节作用及其神经机制。

方法

采用电生理方法,用玻璃微电极记录孤束核(NTS)神经元动作电位的细胞外放电信号。观察针刺“足三里”(ST 36)、“内关”(PC 6)、“中脘”(CV 12)、“气海”(CV 6)对正常生理状态大鼠NTS神经元放电及胃内压的影响,以及胃运动增强或减弱时的影响。

结果

针刺“足三里”(ST 36)、“内关”(PC 6)可显著促进正常状态大鼠的胃动力,增强或减弱胃运动,而针刺“中脘”(CV 12)、“气海”(CV 6)可显著抑制胃运动。针刺上述所有穴位均可激活NTS神经元放电。

结论

穴位的双向调节作用不一定表明同一点在不同病理状态下对内脏有双向调节作用,而可能是不同穴位的综合作用,是对正常状态和内环境稳态的良好调节。

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